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Effects of photobiomodulation on interleukin-10 and nitrites in individuals with relapsing-remitting multiple sclerosis - Randomized clinical trial.

Tamiris SilvaYara Dadalti FragosoMaria Fernanda Setúbal Destro RodriguesAndréa Oliver GomesFernanda Cordeiro da SilvaLucas Andreo Dias Dos SantosAriane VianaDaniela de Fátima Teixeira da SilvaMaria Cristina ChavantesAnna Carolina Ratto Tempestini HorlianaKátia De AngelisAlessandro Melo DeanaLuciana Prats BrancoKristianne Porta Santos FernandesLara Jansiski MottaRaquel Agnelli Mesquita-FerrariSandra Kalil Bussadori
Published in: PloS one (2020)
Treatment with PBM positively modulated the expression of IL-10 but had no effect on nitrite levels. Further studies should be conducted with a larger sample and a control group, as PBM may be a promising complementary treatment for the management of MS. This trial is registered at ClinicalTrials.gov. Identifier: NCT03360487.
Keyphrases
  • multiple sclerosis
  • white matter
  • nitric oxide
  • poor prognosis
  • clinical trial
  • randomized controlled trial
  • phase iii
  • phase ii
  • open label
  • replacement therapy