Identifying digital biomarkers of illness activity and treatment response in bipolar disorder with a novel wearable device (TIMEBASE): protocol for a pragmatic observational clinical study.
Gerard AnmellaFilippo CorponiBryan M LiAriadna MasMarina GarrigaMiriam SanabraIsabella PacchiarottiMarc ValentíIria GrandeAntonio BenabarreAnna Giménez-PalomoIsabel AgasiAnna BastidasMyriam CaveroMiquel BioqueClemente Garcia-RizoSantiago MaderoNéstor ArbeloAndrea MurruSilvia AmorettiAnabel Martinez-AranVictoria RuizYudit RivasGiovanna FicoMichele De PriscoVincenzo OlivaAleix SolanesJoaquim RaduàLudovic SamalinAllan H YoungAntonio VergariEduard VietaDiego Hidalgo-MazzeiPublished in: BJPsych open (2024)
This project should contribute to understanding the pathophysiology of affective disorders. The potential digital biomarkers of illness activity and treatment response in bipolar disorder could be implemented in a real-world clinical setting for clinical monitoring and identification of prodromal symptoms. This would allow early intervention and prevention of affective relapses, as well as personalisation of treatment.