This review analyzes possibilities and limitations of functional MRI sequences separately to obtain insight in the post-therapy setting. Diffusion, perfusion and spectroscopy show promise, especially when utilized complimentary to each other. These functional MRI sequences aid in the early detection which might improve survival by increasing effectiveness of salvage therapy. Future multicenter longitudinal prospective studies are needed to provide standardized guidelines for the use of functional MRI in daily clinical practice.
Keyphrases
- contrast enhanced
- magnetic resonance imaging
- clinical practice
- diffusion weighted imaging
- randomized controlled trial
- systematic review
- computed tomography
- magnetic resonance
- high resolution
- machine learning
- cross sectional
- clinical trial
- stem cells
- bone marrow
- big data
- deep learning
- artificial intelligence
- cell therapy
- case control
- replacement therapy
- clinical evaluation