Patients with stable coronary artery disease and type 2 diabetes but without prior myocardial infarction or stroke and THEMIS-like patients: real-world prevalence and risk of major outcomes from the SNDS French nationwide claims database.
Patrick BlinPatrice DarmonPatrick HenryEstelle GuiardMarie-Agnès BernardCaroline Dureau-PourninHélène MaiziFlorence Thomas-DelecourtRégis LassalleCécile Droz-PerroteauNicholas MoorePublished in: Cardiovascular diabetology (2021)
THEMIS-like prevalence was estimated at 1.50 per 1,000 adults, representing about a quarter of CAD-T2DM without MI/stroke patients, and 0.27 per 1000 adults for the THEMIS-PCI-like populations. In current French practice, the median age of both these populations was about 5-6 years older than in the THEMIS trial, with a 2-year incidence of major outcomes between two or four time above the ones of the placebo arm of the THEMIS trial using very close definitions. Registration No. EUPAS27402 ( http://www.ENCEPP.eu ).
Keyphrases
- coronary artery disease
- risk factors
- type diabetes
- phase iii
- study protocol
- end stage renal disease
- percutaneous coronary intervention
- atrial fibrillation
- clinical trial
- ejection fraction
- heart failure
- chronic kidney disease
- glycemic control
- primary care
- healthcare
- phase ii
- cardiovascular events
- newly diagnosed
- coronary artery bypass grafting
- physical activity
- acute myocardial infarction
- randomized controlled trial
- cardiovascular disease
- emergency department
- open label
- health insurance
- acute coronary syndrome
- st segment elevation myocardial infarction
- patient reported outcomes
- cross sectional
- st elevation myocardial infarction
- double blind
- antiplatelet therapy
- brain injury
- electronic health record
- community dwelling
- weight loss