A Benzarone Derivative Inhibits EYA to Suppress Tumor Growth in SHH Medulloblastoma.

Grace H Hwang Maria F Pazyra-Murphy Hyuk-Soo Seo Sirano Dhe-Paganon Sylwia A Stopka Marina DiPiazza Nizhoni Sutter Thomas W Gero Alison Volkert Lincoln Ombelets Georgia A Dittemore Matthew G Rees Melissa A Ronan Jennifer A Roth Nathalie Y R Agar David A Scott Rosalind A Segal

Published in: Cancer research (2024)

Development of a benzarone derivative that inhibits EYA1 and impedes the growth of SHH medulloblastoma provides an avenue for improving treatment of this malignant pediatric brain cancer.

Keyphrases

papillary thyroid
squamous cell
white matter
water soluble
cerebral ischemia
replacement therapy
subarachnoid hemorrhage