Hyuk-Soo Seo

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 34

Top Topics

Respiratory Syndrome Coronavirus

Histone Deacetylase

Top Venues

Nature chemical biology

Cancer research

Nature medicine

This page only lists publications with an associated author ORCID identifier.

Publications

Grace H Hwang, Maria F Pazyra-Murphy, Hyuk-Soo Seo, Sirano Dhe-Paganon, Sylwia A Stopka, Marina DiPiazza, Nizhoni Sutter, Thomas W Gero, Alison Volkert, Lincoln Ombelets, Georgia A Dittemore, Matthew G Rees, Melissa A Ronan, Jennifer A Roth, Nathalie Y R Agar, David A Scott, Rosalind A Segal
A Benzarone Derivative Inhibits EYA to Suppress Tumor Growth in SHH Medulloblastoma. Cancer research 84 (6) (2024)
Bee Hui Liu, Miao Liu, Sridhar Radhakrishnan, Chaitanya Kumar Jaladanki, Chong Gao, Jing Ping Tang, Kalpana Kumari, Mei Lin Go, Kim Anh L Vu, Hyuk-Soo Seo, Kijun Song, Xi Tian, Li Feng, Justin L Tan, Mahmoud A Bassal, Haribabu Arthanari, Jun Qi, Sirano Dhe-Paganon, Hao Fan, Daniel Geoffrey Tenen, Li Chai
Targeting transcription factors through an IMiD independent zinc finger domain. bioRxiv : the preprint server for biology (2024)
Grace H Hwang, Maria F Pazyra-Murphy, Hyuk-Soo Seo, Sirano Dhe-Paganon, Sylwia A Stopka, Marina DiPiazza, Nizhoni Sutter, Thomas W Gero, Alison Volkert, Lincoln Ombelets, Georgia A Dittemore, Matthew G Rees, Melissa A Ronan, Jennifer A Roth, Nathalie Y R Agar, David A Scott, Rosalind A Segal
A Benzarone Derivative Inhibits EYA to Suppress Tumor Growth in SHH Medulloblastoma. Cancer research 84 (6) (2024)
Grace H Hwang, Maria F Pazyra-Murphy, Hyuk-Soo Seo, Sirano Dhe-Paganon, Sylwia A Stopka, Marina DiPiazza, Nizhoni Sutter, Thomas W Gero, Alison Volkert, Lincoln Ombelets, Georgia A Dittemore, Matthew G Rees, Melissa A Ronan, Jennifer A Roth, Nathalie Y R Agar, David A Scott, Rosalind A Segal
A Benzarone Derivative Inhibits EYA to Suppress Tumor Growth in SHH Medulloblastoma. Cancer research 84 (6) (2024)
Grace H Hwang, Maria F Pazyra-Murphy, Hyuk-Soo Seo, Sirano Dhe-Paganon, Sylwia A Stopka, Marina DiPiazza, Nizhoni Sutter, Thomas W Gero, Alison Volkert, Lincoln Ombelets, Georgia A Dittemore, Matthew G Rees, Melissa A Ronan, Jennifer A Roth, Nathalie Y R Agar, David A Scott, Rosalind A Segal
A Benzarone Derivative Inhibits EYA to Suppress Tumor Growth in SHH Medulloblastoma. Cancer research 84 (6) (2024)
Narek Darabedian, Wenzhi Ji, Mengyang Fan, Shan Lin, Hyuk-Soo Seo, Ekaterina V Vinogradova, Tomer M Yaron, Evanna L Mills, Haopeng Xiao, Kristine Senkane, Emily M Huntsman, Jared L Johnson, Jianwei Che, Lewis C Cantley, Benjamin F Cravatt, Sirano Dhe-Paganon, Kimberly Stegmaier, Tinghu Zhang, Nathanael S Gray, Edward T Chouchani
Depletion of creatine phosphagen energetics with a covalent creatine kinase inhibitor. Nature chemical biology (2023)
Etsuro Nanishi, Francesco Borriello, Hyuk-Soo Seo, Timothy R O'Meara, Marisa E McGrath, Yoshine Saito, Jing Chen, Joann Diray-Arce, Kijun Song, Andrew Z Xu, Soumik Barman, Manisha Menon, Danica Dong, Timothy M Caradonna, Jared Feldman, Blake M Hauser, Aaron G Schmidt, Lindsey R Baden, Robert K Ernst, Carly Dillen, Jingyou Yu, Aiquan Chang, Luuk Hilgers, Peter Paul Platenburg, Sirano Dhe-Paganon, Dan H Barouch, Al Ozonoff, Ivan Zanoni, Matthew B Friemann, David J Dowling, Ofer Levy
Carbohydrate fatty acid monosulphate: oil-in-water adjuvant enhances SARS-CoV-2 RBD nanoparticle-induced immunogenicity and protection in mice. NPJ vaccines 8 (1) (2023)
Weihai Liu, Yun Wang, Luiz H M Bozi, Patrick D Fischer, Mark P Jedrychowski, Haopeng Xiao, Tao Wu, Narek Darabedian, Xiadi He, Evanna L Mills, Nils Burger, Sanghee Shin, Anita Reddy, Hans-Georg Sprenger, Nhien Tran, Sally Winther, Stephen M Hinshaw, Jingnan Shen, Hyuk-Soo Seo, Kijun Song, Andrew Z Xu, Luke Sebastian, Jean J Zhao, Sirano Dhe-Paganon, Jianwei Che, Steven P Gygi, Haribabu Arthanari, Edward T Chouchani
Lactate regulates cell cycle by remodeling the anaphase promoting complex. Nature (2023)
Etsuro Nanishi, Francesco Borriello, Hyuk-Soo Seo, Timothy R O'Meara, Marisa E McGrath, Yoshine Saito, Jing Chen, Joann Diray-Arce, Kijun Song, Andrew Z Xu, Soumik Barman, Manisha Menon, Danica Dong, Timothy M Caradonna, Jared Feldman, Blake M Hauser, Aaron G Schmidt, Lindsey R Baden, Robert K Ernst, Carly Dillen, Jingyou Yu, Aiquan Chang, Luuk Hilgers, Peter Paul Platenburg, Sirano Dhe-Paganon, Dan H Barouch, Al Ozonoff, Ivan Zanoni, Matthew B Friemann, David J Dowling, Ofer Levy
Carbohydrate fatty acid monosulphate: oil-in-water adjuvant enhances SARS-CoV-2 RBD nanoparticle-induced immunogenicity and protection in mice. NPJ vaccines 8 (1) (2023)
Etsuro Nanishi, Francesco Borriello, Hyuk-Soo Seo, Timothy R O'Meara, Marisa E McGrath, Yoshine Saito, Jing Chen, Joann Diray-Arce, Kijun Song, Andrew Z Xu, Soumik Barman, Manisha Menon, Danica Dong, Timothy M Caradonna, Jared Feldman, Blake M Hauser, Aaron G Schmidt, Lindsey R Baden, Robert K Ernst, Carly Dillen, Jingyou Yu, Aiquan Chang, Luuk Hilgers, Peter Paul Platenburg, Sirano Dhe-Paganon, Dan H Barouch, Al Ozonoff, Ivan Zanoni, Matthew B Friemann, David J Dowling, Ofer Levy
Publisher Correction: Carbohydrate fatty acid monosulphate: oil-in-water adjuvant enhances SARS-CoV-2 RBD nanoparticle-induced immunogenicity and protection in mice. NPJ vaccines 8 (1) (2023)
Etsuro Nanishi, Francesco Borriello, Hyuk-Soo Seo, Timothy R O'Meara, Marisa E McGrath, Yoshine Saito, Jing Chen, Joann Diray-Arce, Kijun Song, Andrew Z Xu, Soumik Barman, Manisha Menon, Danica Dong, Timothy M Caradonna, Jared Feldman, Blake M Hauser, Aaron G Schmidt, Lindsey R Baden, Robert K Ernst, Carly Dillen, Jingyou Yu, Aiquan Chang, Luuk Hilgers, Peter Paul Platenburg, Sirano Dhe-Paganon, Dan H Barouch, Al Ozonoff, Ivan Zanoni, Matthew B Friemann, David J Dowling, Ofer Levy
Carbohydrate fatty acid monosulphate: oil-in-water adjuvant enhances SARS-CoV-2 RBD nanoparticle-induced immunogenicity and protection in mice. NPJ vaccines 8 (1) (2023)
Narek Darabedian, Wenzhi Ji, Mengyang Fan, Shan Lin, Hyuk-Soo Seo, Ekaterina V Vinogradova, Tomer M Yaron, Evanna L Mills, Haopeng Xiao, Kristine Senkane, Emily M Huntsman, Jared L Johnson, Jianwei Che, Lewis C Cantley, Benjamin F Cravatt, Sirano Dhe-Paganon, Kimberly Stegmaier, Tinghu Zhang, Nathanael S Gray, Edward T Chouchani
Depletion of creatine phosphagen energetics with a covalent creatine kinase inhibitor. Nature chemical biology (2023)
Etsuro Nanishi, Francesco Borriello, Hyuk-Soo Seo, Timothy R O'Meara, Marisa E McGrath, Yoshine Saito, Jing Chen, Joann Diray-Arce, Kijun Song, Andrew Z Xu, Soumik Barman, Manisha Menon, Danica Dong, Timothy M Caradonna, Jared Feldman, Blake M Hauser, Aaron G Schmidt, Lindsey R Baden, Robert K Ernst, Carly Dillen, Jingyou Yu, Aiquan Chang, Luuk Hilgers, Peter Paul Platenburg, Sirano Dhe-Paganon, Dan H Barouch, Al Ozonoff, Ivan Zanoni, Matthew B Friemann, David J Dowling, Ofer Levy
Carbohydrate fatty acid monosulphate: oil-in-water adjuvant enhances SARS-CoV-2 RBD nanoparticle-induced immunogenicity and protection in mice. NPJ vaccines 8 (1) (2023)
Raaj S Mehta, Jared R Mayers, Yancong Zhang, Amrisha Bhosle, Nathaniel R Glasser, Long H Nguyen, Wenjie Ma, Sena Bae, Tobyn Branck, Kijun Song, Luke Sebastian, Julian Avila Pacheco, Hyuk-Soo Seo, Andrew T Chan, Sirano Dhe-Paganon, Ashwin N Ananthakrishnan, Eric A Franzosa, Emily P Balskus, Andrew T Chan, Curtis Huttenhower
Gut microbial metabolism of 5-ASA diminishes its clinical efficacy in inflammatory bowel disease. Nature medicine (2023)
Etsuro Nanishi, Francesco Borriello, Hyuk-Soo Seo, Timothy R O'Meara, Marisa E McGrath, Yoshine Saito, Jing Chen, Joann Diray-Arce, Kijun Song, Andrew Z Xu, Soumik Barman, Manisha Menon, Danica Dong, Timothy M Caradonna, Jared Feldman, Blake M Hauser, Aaron G Schmidt, Lindsey R Baden, Robert K Ernst, Carly Dillen, Jingyou Yu, Aiquan Chang, Luuk Hilgers, Peter Paul Platenburg, Sirano Dhe-Paganon, Dan H Barouch, Al Ozonoff, Ivan Zanoni, Matthew B Friemann, David J Dowling, Ofer Levy
Publisher Correction: Carbohydrate fatty acid monosulphate: oil-in-water adjuvant enhances SARS-CoV-2 RBD nanoparticle-induced immunogenicity and protection in mice. NPJ vaccines 8 (1) (2023)
Raaj S Mehta, Jared R Mayers, Yancong Zhang, Amrisha Bhosle, Nathaniel R Glasser, Long H Nguyen, Wenjie Ma, Sena Bae, Tobyn Branck, Kijun Song, Luke Sebastian, Julian Avila Pacheco, Hyuk-Soo Seo, Andrew T Chan, Sirano Dhe-Paganon, Ashwin N Ananthakrishnan, Eric A Franzosa, Emily P Balskus, Andrew T Chan, Curtis Huttenhower
Gut microbial metabolism of 5-ASA diminishes its clinical efficacy in inflammatory bowel disease. Nature medicine 29 (3) (2023)
Etsuro Nanishi, Francesco Borriello, Hyuk-Soo Seo, Timothy R O'Meara, Marisa E McGrath, Yoshine Saito, Jing Chen, Joann Diray-Arce, Kijun Song, Andrew Z Xu, Soumik Barman, Manisha Menon, Danica Dong, Timothy M Caradonna, Jared Feldman, Blake M Hauser, Aaron G Schmidt, Lindsey R Baden, Robert K Ernst, Carly Dillen, Jingyou Yu, Aiquan Chang, Luuk Hilgers, Peter Paul Platenburg, Sirano Dhe-Paganon, Dan H Barouch, Al Ozonoff, Ivan Zanoni, Matthew B Friemann, David J Dowling, Ofer Levy
Publisher Correction: Carbohydrate fatty acid monosulphate: oil-in-water adjuvant enhances SARS-CoV-2 RBD nanoparticle-induced immunogenicity and protection in mice. NPJ vaccines 8 (1) (2023)
Etsuro Nanishi, Francesco Borriello, Hyuk-Soo Seo, Timothy R O'Meara, Marisa E McGrath, Yoshine Saito, Jing Chen, Joann Diray-Arce, Kijun Song, Andrew Z Xu, Soumik Barman, Manisha Menon, Danica Dong, Timothy M Caradonna, Jared Feldman, Blake M Hauser, Aaron G Schmidt, Lindsey R Baden, Robert K Ernst, Carly Dillen, Jingyou Yu, Aiquan Chang, Luuk Hilgers, Peter Paul Platenburg, Sirano Dhe-Paganon, Dan H Barouch, Al Ozonoff, Ivan Zanoni, Matthew B Friemann, David J Dowling, Ofer Levy
Carbohydrate fatty acid monosulphate: oil-in-water adjuvant enhances SARS-CoV-2 RBD nanoparticle-induced immunogenicity and protection in mice. NPJ vaccines 8 (1) (2023)
Raaj S Mehta, Jared R Mayers, Yancong Zhang, Amrisha Bhosle, Nathaniel R Glasser, Long H Nguyen, Wenjie Ma, Sena Bae, Tobyn Branck, Kijun Song, Luke Sebastian, Julian Avila Pacheco, Hyuk-Soo Seo, Andrew T Chan, Sirano Dhe-Paganon, Ashwin N Ananthakrishnan, Eric A Franzosa, Emily P Balskus, Andrew T Chan, Curtis Huttenhower
Gut microbial metabolism of 5-ASA diminishes its clinical efficacy in inflammatory bowel disease. Nature medicine 29 (3) (2023)
Eshini Panditharatna, Joana G Marques, Tingjian Wang, Maria C Trissal, Ilon Liu, Li Jiang, Alexander Beck, Andrew Groves, Neekesh V Dharia, Deyao Li, Samantha E Hoffman, Guillaume Kugener, McKenzie L Shaw, Hafsa M Mire, Olivia A Hack, Joshua M Dempster, Caleb A Lareau, Lingling Dai, Logan H Sigua, Michael A Quezada, Ann-Catherine J Stanton, Meghan Wyatt, Zohra Kalani, Amy Goodale, Francisca Vazquez, Frederica Piccioni, John G Doench, David E Root, Jamie N Anastas, Kristen L Jones, Amy Saur Conway, Sylwia A Stopka, Michael S Regan, Yu Liang, Hyuk-Soo Seo, Kijun Song, Puspalata Bashyal, William P Jerome, Nathan D Mathewson, Sirano Dhe-Paganon, Mario L Suvà, Angel Montero Carcaboso, Cinzia Lavarino, Jaume Catala-Mora, Quang-De Nguyen, Keith L Ligon, Yang Shi, Sameer Agnihotri, Nathalie Y R Agar, Kimberly Stegmaier, Charles D Stiles, Michelle Monje, Todd R Golub, Jun Qi, Mariella G Filbin
BAF Complex Maintains Glioma Stem Cells in Pediatric H3K27M Glioma. Cancer discovery 12 (12) (2022)
Etsuro Nanishi, Marisa E McGrath, Timothy R O'Meara, Soumik Barman, Jingyou Yu, Huahua Wan, Carly A Dillen, Manisha Menon, Hyuk-Soo Seo, Kijun Song, Andrew Z Xu, Luke Sebastian, Byron Brook, Anna-Nicole Bosco, Francesco Borriello, Robert K Ernst, Dan H Barouch, Sirano Dhe-Paganon, Ofer Levy, Matthew B Friemann, David J Dowling
mRNA booster vaccination protects aged mice against the SARS-CoV-2 Omicron variant. Communications biology 5 (1) (2022)
Katherine Chew, Branden Lee, Simon Daniel van Haren, Etsuro Nanishi, Timothy R O'Meara, Jennifer B Splaine, Maria DeLeon, Dheeraj Soni, Hyuk-Soo Seo, Sirano Dhe-Paganon, Al Ozonoff, Jennifer A Smith, Ofer Levy, David J Dowling
Adjuvant Discovery via a High Throughput Screen using Human Primary Mononuclear Cells. bioRxiv : the preprint server for biology (2022)
Helen Tanton, Tomasz Sewastianik, Hyuk-Soo Seo, David Remillard, Roodolph St Pierre, Pratyusha Bala, Daulet Aitymbayev, Peter Dennis, Keith Adler, Ezekiel Geffken, Zoe Yeoh, Nicholas Vangos, Filip Garbicz, David A Scott, Nilay S Sethi, James E Bradner, Sirano Dhe-Paganon, Ruben D Carrasco
A novel β-catenin/BCL9 complex inhibitor blocks oncogenic Wnt signaling and disrupts cholesterol homeostasis in colorectal cancer. Science advances 8 (17) (2022)
Michelle S Prew, Christina M Camara, Thomas Botzanowski, Jamie A Moroco, Noah B Bloch, Hannah R Levy, Hyuk-Soo Seo, Sirano Dhe-Paganon, Gregory H Bird, Henry D Herce, Micah A Gygi, Silvia Escudero, Thomas E Wales, John R Engen, Loren D Walensky
Structural basis for defective membrane targeting of mutant enzyme in human VLCAD deficiency. Nature communications 13 (1) (2022)
Mingxing Teng, Jie Jiang, Scott B Ficarro, Hyuk-Soo Seo, Jae Hyun Bae, Katherine Aleisha Donovan, Eric S Fischer, Tinghu Zhang, Sirano Dhe-Paganon, Jarrod A Marto, Nathanael S Gray
Exploring Ligand-Directed N-Acyl-N-alkylsulfonamide-Based Acylation Chemistry for Potential Targeted Degrader Development. ACS medicinal chemistry letters 12 (8) (2021)
Christian Dubiella, Benika J Pinch, Kazuhiro Koikawa, Daniel Zaidman, Evon Poon, Theresa D Manz, Behnam Nabet, Shuning He, Efrat Resnick, Adi Rogel, Ellen M Langer, Colin J Daniel, Hyuk-Soo Seo, Ying Chen, Guillaume Adelmant, Shabnam Sharifzadeh, Scott B Ficarro, Yann Jamin, Barbara Martins da Costa, Mark W Zimmerman, Xiaolan Lian, Shin Kibe, Shingo Kozono, Zainab M Doctor, Christopher M Browne, Annan Yang, Liat Stoler-Barak, Richa B Shah, Nicholas E Vangos, Ezekiel A Geffken, Roni Oren, Eriko Koide, Samuel Sidi, Ziv Shulman, Chu Wang, Jarrod A Marto, Sirano Dhe-Paganon, Thomas Look, Xiao Zhen Zhou, Kun Ping Lu, Rosalie C Sears, Louis Chesler, Nathanael S Gray, Nir London
Sulfopin is a covalent inhibitor of Pin1 that blocks Myc-driven tumors in vivo. Nature chemical biology 17 (9) (2021)
Theresa D Manz, Sindhu Carmen Sivakumaren, Fleur M Ferguson, Tinghu Zhang, Adam Yasgar, Hyuk-Soo Seo, Scott B Ficarro, Joseph D Card, Hyeseok Shim, Chandrasekhar V Miduturu, Anton Simeonov, Min Shen, Jarrod A Marto, Sirano Dhe-Paganon, Matthew D Hall, Lewis C Cantley, Nathanael S Gray
Discovery and Structure-Activity Relationship Study of (Z)-5-Methylenethiazolidin-4-one Derivatives as Potent and Selective Pan-phosphatidylinositol 5-Phosphate 4-Kinase Inhibitors. Journal of medicinal chemistry 63 (9) (2020)
Matthew J McBride, Nazar Mashtalir, Evan B Winter, Hai T Dao, Martin Filipovski, Andrew R D'Avino, Hyuk-Soo Seo, Neil T Umbreit, Roodolph St Pierre, Alfredo M Valencia, Kristin Qian, Hayley J Zullow, Jacob D Jaffe, Sirano Dhe-Paganon, Tom W Muir, Cigall Kadoch
Author Correction: The nucleosome acidic patch and H2A ubiquitination underlie mSWI/SNF recruitment in synovial sarcoma. Nature structural & molecular biology (2020)
Accalia Fu, Juan Carlos Alvarez-Perez, Daina Avizonis, Tatsuya Kin, Scott B Ficarro, Dong Wook Choi, Esra Karakose, Mehmet G Badur, Lindsay Evans, Carolina Rosselot, Gaelle Bridon, Gregory H Bird, Hyuk-Soo Seo, Sirano Dhe-Paganon, Jurre J Kamphorst, Andrew F Stewart, A M James Shapiro, Jarrod A Marto, Loren D Walensky, Russell G Jones, Adolfo Garcia-Ocana, Nika N Danial
Glucose-dependent partitioning of arginine to the urea cycle protects β-cells from inflammation. Nature metabolism 2 (5) (2020)
Benika J Pinch, Zainab M Doctor, Behnam Nabet, Christopher M Browne, Hyuk-Soo Seo, Mikaela L Mohardt, Shingo Kozono, Xiaolan Lian, Theresa D Manz, Yujin Chun, Shin Kibe, Daniel Zaidman, Dina Daitchman, Zoe C Yeoh, Nicholas E Vangos, Ezekiel A Geffken, Li Tan, Scott B Ficarro, Nir London, Jarrod A Marto, Stephen Buratowski, Sirano Dhe-Paganon, Xiao Zhen Zhou, Kun Ping Lu, Nathanael S Gray
Identification of a potent and selective covalent Pin1 inhibitor. Nature chemical biology 16 (9) (2020)
Matthew J McBride, Nazar Mashtalir, Evan B Winter, Hai T Dao, Martin Filipovski, Andrew R D'Avino, Hyuk-Soo Seo, Neil T Umbreit, Roodolph St Pierre, Alfredo M Valencia, Kristin Qian, Hayley J Zullow, Jacob D Jaffe, Sirano Dhe-Paganon, Tom W Muir, Cigall Kadoch
The nucleosome acidic patch and H2A ubiquitination underlie mSWI/SNF recruitment in synovial sarcoma. Nature structural & molecular biology 27 (9) (2020)
Elvin Dominic de Araujo, Fettah Erdogan, Heidi A Neubauer, Deniz Meneksedag-Erol, Pimyupa Manaswiyoungkul, Mohammad S Eram, Hyuk-Soo Seo, Abdul K Qadree, Johan Israelian, Anna Orlova, Tobias Suske, Ha Thi Thanh Pham, Auke Boersma, Simone Tangermann, Lukas Kenner, Thomas Rülicke, Aiping Dong, Manimekalai Ravichandran, Peter J Brown, Gerald F Audette, Sarah Rauscher, Sirano Dhe-Paganon, Richard H Moriggl, Patrick T Gunning
Structural and functional consequences of the STAT5BN642H driver mutation. Nature communications 10 (1) (2019)
Elvin D de Araujo, Anna Orlova, Heidi A Neubauer, Dávid Bajusz, Hyuk-Soo Seo, Sirano Dhe-Paganon, György M Keserű, Richard Moriggl, Patrick T Gunning
Structural Implications of STAT3 and STAT5 SH2 Domain Mutations. Cancers 11 (11) (2019)
Bartlomiej Jan Blus, Junseock Koh, Aleksandra Krolak, Hyuk-Soo Seo, Elias Coutavas, Günter Blobel
Allosteric modulation of nucleoporin assemblies by intrinsically disordered regions. Science advances 5 (11) (2019)