Vascular disease and apathy symptoms in the very old: A cross-sectional and longitudinal meta-analysis of individual participant data.

Veerle M G T H van der KleiRosalinde K E PoortvlietJonathan M K BogaertsJeanet W BlomSimon P MooijaartRuth TehMarama Muru-LanningLeah PalaparAndrew KingstonLouise RobinsonNgaire KerseJacobijn Gussekloo

Published in: International journal of geriatric psychiatry (2022)

Vascular disease in the very old is associated with apathy symptoms cross-sectionally, but not proven longitudinally, independent of depressive symptoms. These findings query a vascular cause underlying apathy symptoms. However, the consistency of our cross-sectional findings in direction and magnitude across the TULIPS-consortium do emphasize international relevance of the interplay of vascular factors and apathy in advanced age, which meaning needs further unravelling.

Keyphrases

cross sectional
depressive symptoms
sleep quality
social support
machine learning
big data
artificial intelligence
data analysis