The m 6 A modification mediated-lncRNA POU6F2-AS1 reprograms fatty acid metabolism and facilitates the growth of colorectal cancer via upregulation of FASN.

Tao JiangJunwen QiZhenyu XueBowen LiuJianquan LiuQihang HuYuqiu LiJing RenHu SongYixin XuTeng XuRuizhi FanJun Song

Published in: Molecular cancer (2024)

Our data revealed that the upregulation of POU6F2-AS1 plays a critical role in CRC fatty acid metabolism and might provide a novel promising biomarker and therapeutic target for CRC.

Keyphrases

fatty acid
poor prognosis
cell proliferation
signaling pathway
long non coding rna
electronic health record
single cell
big data
long noncoding rna
data analysis
deep learning