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Improved in vivo PET imaging of the adenosine A2A receptor in the brain using [18F]FLUDA, a deuterated radiotracer with high metabolic stability.

Thu Hang LaiMagali ToussaintRodrigo TeodoroSladjana Dukić-StefanovićDaniel GündelFriedrich-Alexander LudwigBarbara WenzelSusann SchröderBernhard SattlerRareş-Petru MoldovanBjörn H FalkenburgerOsama SabriWinnie Deuther-ConradPeter Brust
Published in: European journal of nuclear medicine and molecular imaging (2021)
The new radiotracer [18F]FLUDA is suitable to detect the availability of the A2A receptor in the brain with high target specificity. It is regarded ready for human application.
Keyphrases
  • pet imaging
  • resting state
  • white matter
  • positron emission tomography
  • endothelial cells
  • cerebral ischemia
  • computed tomography
  • multiple sclerosis
  • pluripotent stem cells