The Australasian Resuscitation In Sepsis Evaluation: FLUid or vasopressors In Emergency Department Sepsis, a multicentre observational study (ARISE FLUIDS observational study): Rationale, methods and analysis plan.
Gerben KeijzersStephen Pj MacDonaldAndrew A UdyArendts GlennMichael BaileyRinaldo BellomoGabriel Elan BlecherJonathon BurchamAnthony DelaneyAndrew R CogginsDaniel Michael FatovichJohn F FraserAmanda HarleyPeter G JonesFran KinnearKatya MaySandra PeakeDavid McDonald TaylorJulian WilliamsPatricia Williamsnull nullPublished in: Emergency medicine Australasia : EMA (2019)
This multicentre, observational study will provide insight into current haemodynamic resuscitation practices in patients with sepsis and hypotension as well as estimates of practice variation and patient outcomes. The results will inform the design and feasibility of a multicentre phase III trial of early haemodynamic resuscitation in patients presenting to ED with sepsis and hypotension.
Keyphrases
- septic shock
- phase iii
- clinical trial
- emergency department
- study protocol
- cardiac arrest
- double blind
- intensive care unit
- acute kidney injury
- open label
- primary care
- healthcare
- end stage renal disease
- phase ii
- cross sectional
- newly diagnosed
- cardiopulmonary resuscitation
- randomized controlled trial
- chronic kidney disease
- prognostic factors
- patient reported outcomes