SNHG15 is a negative regulator of inflammation by mediating TRAF2 ubiquitination in stroke-induced immunosuppression.
Huiling SunShuo LiZhaohan XuChengfang LiuPengyu GongJunshan ZhouFuling YanPublished in: Journal of neuroinflammation (2022)
This study identified SNHG15 as a negative regulator of inflammation in stroke-induced immunosuppression, suggesting it as a novel biomarker and therapeutic target in stroke-associated infection. Trial registration ClinicalTrials.gov NCT04175691. Registered November 25, 2019, https://www.clinicaltrials.gov/ct2/show/NCT04175691 .
Keyphrases
- atrial fibrillation
- oxidative stress
- diabetic rats
- high glucose
- poor prognosis
- transcription factor
- computed tomography
- clinical trial
- drug induced
- magnetic resonance imaging
- study protocol
- randomized controlled trial
- cerebral ischemia
- endothelial cells
- image quality
- blood brain barrier
- brain injury
- subarachnoid hemorrhage
- stress induced