A Randomized, Double-Blind, Sham-Controlled, Clinical Trial of Auricular Vagus Nerve Stimulation for the Treatment of Active Rheumatoid Arthritis.

Matthew C BakerSarah KavanaghStanley B CohenAlan K MatsumotoAra DikranianJohn TesserAlan KivitzKonstantinos AlatarisMark C Genovese

Published in: Arthritis & rheumatology (Hoboken, N.J.) (2023)

Auricular VNS did not meaningfully improve RA disease activity. If VNS with other modalities is pursued in the future for the treatment of RA, larger, controlled studies will be needed to understand its utility. This article is protected by copyright. All rights reserved.

Keyphrases

disease activity
rheumatoid arthritis
clinical trial
systemic lupus erythematosus
ankylosing spondylitis
double blind
rheumatoid arthritis patients
study protocol
randomized controlled trial
phase ii
open label
phase iii
combination therapy
smoking cessation
systemic sclerosis