Multicenter clinical trial on sentinel lymph node biopsy using superparamagnetic iron oxide nanoparticles and a novel handheld magnetic probe.
Kanae TarunoTomoko KuritaAkihiko KuwahataKeiko YanagiharaKatsutoshi EnokidoYoshihisa KatayoseSeigo NakamuraHiroyuki TakeiMasaki SekinoMoriaki KusakabePublished in: Journal of surgical oncology (2019)
This was the first clinical study to use a novel handheld magnetometer to detect SLN, which we demonstrate to be not inferior to the RI method.
Keyphrases
- iron oxide nanoparticles
- sentinel lymph node
- double blind
- clinical trial
- early stage
- lymph node
- neoadjuvant chemotherapy
- placebo controlled
- phase ii
- phase iii
- study protocol
- molecularly imprinted
- quantum dots
- living cells
- open label
- cross sectional
- randomized controlled trial
- squamous cell carcinoma
- radiation therapy
- locally advanced
- fluorescent probe
- tandem mass spectrometry