Lactobacillus group and arterial hypertension: A broad review on effects and proposed mechanisms.
Danilo Duarte de Assis GadelhaJosé Luiz de Brito AlvesPaulo César Trindade da CostaMickael Sousa da LuzClênia de Oliveira CavalcantiFabrícia França BezerrilJuliana Franco AlmeidaJosiane de Campos CruzMarciane MagnaniCamille Moura BalariniSandra Rodrigues MascarenhasValdir de Andrade BragaMaria do Socorro de França-FalcãoPublished in: Critical reviews in food science and nutrition (2022)
Hypertension is the leading risk factor for cardiovascular diseases and is associated with intestinal dysbiosis with a decrease in beneficial microbiota. Probiotics can positively modulate the impaired microbiota and impart benefits to the cardiovascular system. Among them, the emended Lactobacillus has stood out as a microorganism capable of reducing blood pressure, being the target of several studies focused on managing hypertension. This review aimed to present the potential of Lactobacillus as an antihypertensive non-pharmacological strategy. We will address preclinical and clinical studies that support this proposal and the mechanisms of action by which these microorganisms reduce blood pressure or prevent its elevation.