A Study on the Contributions of Sonication to the Identification of Bacteria Associated with Intubation Cannula Biofilm and the Risk of Ventilator-Associated Pneumonia.
Ioana Roxana CodruMihai SavaBogdan Ioan VintilăAlina Simona BereanuVictoria BîrluțiuPublished in: Medicina (Kaunas, Lithuania) (2023)
Ventilator-associated pneumonia is one of the most severe complications of critically ill patients that need mechanical respiratory support, as it poses a significant risk of prolonging hospitalization, disability, and even death. This is why physicians worldwide target newer methods for prevention, early diagnosis, and early target treatment for this condition. There are few methods for a quick etiological diagnosis of pneumonia, especially point of care, and most are only readily available in some intensive care units. This is why a new, simple, and cheap method is needed for determining the bacteria that might be infectious in a particular patient. The manner in question is sonication. Method: In this prospective, observational, single-center study, endotracheal cannula specimens will be collected from at least 100 patients in our intensive care unit. This specimen will be submitted to a specific sonication protocol for bacteria to dislodge the biofilm inside the cannula. The resulting liquid will be seeded on growth media, and then a comparison will be made between the germs in the biofilm and the ones in the tracheal secretion of the patient. The primary purpose is to determine the bacteria before the appearance of a manifest infection.
Keyphrases
- intensive care unit
- respiratory failure
- pseudomonas aeruginosa
- staphylococcus aureus
- mechanical ventilation
- candida albicans
- extracorporeal membrane oxygenation
- end stage renal disease
- case report
- biofilm formation
- primary care
- ejection fraction
- positive airway pressure
- randomized controlled trial
- chronic kidney disease
- multiple sclerosis
- cardiac arrest
- prognostic factors
- peritoneal dialysis
- acute respiratory distress syndrome
- cystic fibrosis
- obstructive sleep apnea
- early onset
- risk factors
- cross sectional
- escherichia coli
- community acquired pneumonia
- ionic liquid
- combination therapy
- ultrasound guided