Putative positive role of inflammatory genes in fat deposition supported by altered gene expression in purified human adipocytes and preadipocytes from lean and obese adipose tissues.
Sang-Hyeop LeeNak-Hyeon ChoiIn-Uk KohBong-Jo KimSong LeeSong-Cheol KimSun Shim ChoiPublished in: Journal of translational medicine (2020)
Taken together, our analyses suggest that inflammatory genes are expressed at lower levels in obese ACs than in lean ACs because lean adipogenesis involves even greater enhancement of inflammatory responses than does obese adipogenesis.
Keyphrases
- adipose tissue
- gene expression
- weight loss
- acute coronary syndrome
- insulin resistance
- metabolic syndrome
- genome wide
- bone mineral density
- type diabetes
- obese patients
- endothelial cells
- oxidative stress
- high fat diet induced
- dna methylation
- genome wide identification
- bioinformatics analysis
- bariatric surgery
- fatty acid
- pluripotent stem cells