A pathway for Parkinson's Disease LRRK2 kinase to block primary cilia and Sonic hedgehog signaling in the brain.

Herschel S Dhekne Izumi Yanatori Rachel C GomezFrancesca TonelliFederico DiezBirgitt SchüleMartin Steger Dario R Alessi Suzanne R Pfeffer

Published in: eLife (2018)

This article has been through an editorial process in which the authors decide how to respond to the issues raised during peer review. The Reviewing Editor's assessment is that all the issues have been addressed (see decision letter).

Keyphrases

white matter
resting state
tyrosine kinase
decision making
multiple sclerosis