Suzanne R Pfeffer

Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 25

Top Venues

eLife

Proceedings of the National Academy of Sciences of the United States of America

bioRxiv : the preprint server for biology

The Journal of cell biology

Stanford University School of Medicine

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Stanford University School of Medicine Jan 01 1986

United States

Professor :: Department of Biochemistry

Publications

Shahzad S Khan, Ebsy Jaimon, Yu-En Lin, Jonas M Nikoloff, Francesca Tonelli, Dario R Alessi, Suzanne R Pfeffer
Loss of primary cilia and dopaminergic neuroprotection in pathogenic LRRK2-driven and idiopathic Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America 121 (32) (2024)
Shahzad S Khan, Ebsy Jaimon, Yu-En Lin, Jonas M Nikoloff, Francesca Tonelli, Dario R Alessi, Suzanne R Pfeffer
Loss of primary cilia and dopaminergic neuroprotection in pathogenic LRRK2-driven and idiopathic Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America 121 (32) (2024)
Shahzad S Khan, Ebsy Jaimon, Yu-En Lin, Jonas M Nikoloff, Francesca Tonelli, Dario R Alessi, Suzanne R Pfeffer
Loss of primary cilia and dopaminergic neuroprotection in pathogenic LRRK2-driven and idiopathic Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America 121 (32) (2024)
Shahzad S Khan, Ebsy Jaimon, Yu-En Lin, Jonas M Nikoloff, Francesca Tonelli, Dario R Alessi, Suzanne R Pfeffer
Loss of primary cilia and dopaminergic neuroprotection in pathogenic LRRK2-driven and idiopathic Parkinson's disease. bioRxiv : the preprint server for biology (2024)
Shahzad S Khan, Ebsy Jaimon, Yu-En Lin, Jonas M Nikoloff, Francesca Tonelli, Dario R Alessi, Suzanne R Pfeffer
Loss of primary cilia and dopaminergic neuroprotection in pathogenic LRRK2-driven and idiopathic Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America 121 (32) (2024)
Shahzad S Khan, Ebsy Jaimon, Yu-En Lin, Jonas M Nikoloff, Francesca Tonelli, Dario R Alessi, Suzanne R Pfeffer
Loss of primary cilia and dopaminergic neuroprotection in pathogenic LRRK2-driven and idiopathic Parkinson's disease. bioRxiv : the preprint server for biology (2024)
Shahzad S Khan, Ebsy Jaimon, Yu-En Lin, Jonas M Nikoloff, Francesca Tonelli, Dario R Alessi, Suzanne R Pfeffer
Loss of primary cilia and dopaminergic neuroprotection in pathogenic LRRK2-driven and idiopathic Parkinson's disease. bioRxiv : the preprint server for biology (2024)
Herschel S Dhekne, Francesca Tonelli, Wondwossen M Yeshaw, Claire Y Chiang, Charles Limouse, Ebsy Jaimon, Elena Purlyte, Dario R Alessi, Suzanne R Pfeffer
Genome-wide screen reveals Rab12 GTPase as a critical activator of Parkinson's disease-linked LRRK2 kinase. eLife 12 (2023)
Prosenjit Pal, Matthew Taylor, Yuko P Y Lam, Francesca Tonelli, Chloe A Hecht, Pawel Lis, Raja S Nirujogi, Toan K Phung, Wondwossen M Yeshaw, Ebsy Jaimon, Rotimi Yemi Fasimoye, Emily A Dickie, Melanie Wightman, Thomas J Macartney, Suzanne R Pfeffer, Dario R Alessi
Parkinson's VPS35[D620N] mutation induces LRRK2-mediated lysosomal association of RILPL1 and TMEM55B. Science advances 9 (50) (2023)
Wondwossen M Yeshaw, Ayan Adhikari, Claire Y Chiang, Herschel S Dhekne, Paulina S Wawro, Suzanne R Pfeffer
Localization of PPM1H phosphatase tunes Parkinson's disease-linked LRRK2 kinase-mediated Rab GTPase phosphorylation and ciliogenesis. Proceedings of the National Academy of Sciences of the United States of America 120 (44) (2023)
Edmundo G Vides, Ayan Adhikari, Claire Y Chiang, Pawel Lis, Elena Purlyte, Charles Limouse, Justin L Shumate, Elena Spínola-Lasso, Herschel S Dhekne, Dario R Alessi, Suzanne R Pfeffer
A feed-forward pathway drives LRRK2 kinase membrane recruitment and activation. eLife 11 (2022)
Suzanne R Pfeffer
LRRK2 phosphorylation of Rab GTPases in Parkinson's disease. FEBS letters (2022)
Herschel S Dhekne, Izumi Yanatori, Edmundo G Vides, Yuriko Sobu, Federico Diez, Francesca Tonelli, Suzanne R Pfeffer
LRRK2-phosphorylated Rab10 sequesters Myosin Va with RILPL2 during ciliogenesis blockade. Life science alliance 4 (5) (2021)
Yuriko Sobu, Paulina S Wawro, Herschel S Dhekne, Wondwossen M Yeshaw, Suzanne R Pfeffer
Pathogenic LRRK2 regulates ciliation probability upstream of tau tubulin kinase 2 via Rab10 and RILPL1 proteins. Proceedings of the National Academy of Sciences of the United States of America 118 (10) (2021)
Shahzad S Khan, Yuriko Sobu, Herschel S Dhekne, Francesca Tonelli, Kerryn Berndsen, Dario R Alessi, Suzanne R Pfeffer
Pathogenic LRRK2 control of primary cilia and Hedgehog signaling in neurons and astrocytes of mouse brain. eLife 10 (2021)
Albert Lu, Frank Hsieh, Bikal R Sharma, Sydney R Vaughn, Carles Rentero, Suzanne R Pfeffer
CRISPR screens for lipid regulators reveal a role for ER-bound SNX13 in lysosomal cholesterol export. The Journal of cell biology 221 (2) (2021)
Piyali Saha, Justin L Shumate, Jenna G Caldwell, Nadia Elghobashi-Meinhardt, Albert Lu, Lichao Zhang, Niclas E Olsson, Joshua E Elias, Suzanne R Pfeffer
Inter-domain dynamics drive cholesterol transport by NPC1 and NPC1L1 proteins. eLife 9 (2020)
Rachel C Gomez, Paulina S Wawro, Pawel Lis, Dario R Alessi, Suzanne R Pfeffer
Membrane association but not identity is required for LRRK2 activation and phosphorylation of Rab GTPases. The Journal of cell biology 218 (12) (2019)
Kerryn Berndsen, Pawel Lis, Wondwossen M Yeshaw, Paulina S Wawro, Raja S Nirujogi, Melanie Wightman, Thomas Macartney, Mark Dorward, Axel Knebel, Francesca Tonelli, Suzanne R Pfeffer, Dario R Alessi
PPM1H phosphatase counteracts LRRK2 signaling by selectively dephosphorylating Rab proteins. eLife 8 (2019)
Herschel S Dhekne, Izumi Yanatori, Rachel C Gomez, Francesca Tonelli, Federico Diez, Birgitt Schüle, Martin Steger, Dario R Alessi, Suzanne R Pfeffer
A pathway for Parkinson's Disease LRRK2 kinase to block primary cilia and Sonic hedgehog signaling in the brain. eLife 7 (2018)
Albert Lu, Paulina Wawro, David W Morgens, Fernando Portela, Michael C Bassik, Suzanne R Pfeffer
Genome-wide interrogation of extracellular vesicle biology using barcoded miRNAs. eLife 7 (2018)
Suzanne R Pfeffer
LRRK2 and Rab GTPases. Biochemical Society transactions 46 (6) (2018)
Elena Purlyte, Herschel S Dhekne, Adil R Sarhan, Rachel Gomez, Pawel Lis, Melanie Wightman, Terina N Martinez, Francesca Tonelli, Suzanne R Pfeffer, Dario R Alessi
Rab29 activation of the Parkinson's disease-associated LRRK2 kinase. The EMBO journal 37 (1) (2017)
Martin Steger, Federico Diez, Herschel S Dhekne, Pawel Lis, Raja S Nirujogi, Ozge Karayel, Francesca Tonelli, Terina N Martinez, Esben Lorentzen, Suzanne R Pfeffer, Dario R Alessi, Matthias Mann
Systematic proteomic analysis of LRRK2-mediated Rab GTPase phosphorylation establishes a connection to ciliogenesis. eLife 6 (2017)
Jian Li, Suzanne R Pfeffer
Lysosomal membrane glycoproteins bind cholesterol and contribute to lysosomal cholesterol export. eLife 5 (2016)
Peter L Lee, Maikke B Ohlson, Suzanne R Pfeffer
Rab6 regulation of the kinesin family KIF1C motor domain contributes to Golgi tethering. eLife 4 (2015)
Pak-yan Patricia Cheung, Charles Limouse, Hideo Mabuchi, Suzanne R Pfeffer
Protein flexibility is required for vesicle tethering at the Golgi. eLife 4 (2015)

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Publication Activity (10 Years)

Top Topics

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Suzanne R Pfeffer