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Innate and adaptive abnormalities in youth with vertically acquired HIV through a multicentre cohort in Spain.

Itziar Carrasco-GarcíaLaura Tarancon-DiezElena Vázquez-AlejoSantiago Jiménez de OryTalía SainzMiren ApilanezCristina EpalzaSara GuillénJosé Tomás RamosCristina DíezJose Ignacio BernardinoJosé Antonio IribarrenAngielys ZamoraMaria Angeles Muñoz-FernándezMaría Luisa Navarronull null
Published in: Journal of the International AIDS Society (2021)
Immunological changes associated with vertically acquired HIV, characterized by increased activation and exhaustion levels in innate and adaptive immune components, are only partially restored by ART. The CD4/CD8 ratio can be a useful marker of disease progression for routine clinical practice.
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