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EXPRESSION OF E-CADHERIN AND CLAUDIN-3 IN THE COLONIC EPITHELIUM AFTER THE INFLIXIMAB THERAPY: EXPERIMENTAL MODEL OF DISUSE COLITIS.

Antonio José Tiburcio AlvesEduardo Felipe Kim GotoDeivid Ramos Dos SantosFernanda Aparecida DominguesMariane Grandi de ÁvilaClaudio Saddy Rodrigues CoyCarlos Augusto Real Martinez
Published in: Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery (2022)
Infliximab therapy reduces inflammation in the colonic segments excluded from intestinal transit and increases the tissue content of E-cadherin and claudin-3 proteins, especially when used at a concentration of 10 mg/kg/week.
Keyphrases
  • ulcerative colitis
  • poor prognosis
  • oxidative stress
  • randomized controlled trial
  • clinical trial
  • mesenchymal stem cells
  • bone marrow
  • study protocol