Surfaceome CRISPR screen identifies OLFML3 as a rhinovirus-inducible IFN antagonist.

Hong MeiZhao ZhaWei WangYusang XieYuege HuangWenping LiDong WeiXinxin ZhangJieming QuJia Liu

Published in: Genome biology (2021)

Our study suggests that RV-induced OLFML3 expression is an important mechanism for RV to hijack the immune system and underscores surfaceome CRISPR screen in identifying viral host factors.

Keyphrases

genome wide
mycobacterium tuberculosis
genome editing
crispr cas
high throughput
poor prognosis
dna methylation
sars cov
immune response
high glucose
dendritic cells
binding protein
drug induced
oxidative stress
respiratory tract