Digital Gait Measures Capture 1-Year Progression in Early-Stage Spinocerebellar Ataxia Type 2.
Jens SeemannLina DaghsenMatthieu CazierJean-Charles LamyMarie-Laure WelterMartin A GieseMatthis SynofzikAlexandra DurrWinfried IlgGiulia CoarelliPublished in: Movement disorders : official journal of the Movement Disorder Society (2024)
Gait measures assessed by wearable sensors can capture natural progression in early-stage SCA2 within just 1 year-in contrast to a clinical ataxia outcome. Lateral step deviation represents a promising outcome measure for upcoming multicenter interventional trials, particularly in the early stages of cerebellar ataxia. © 2024 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.