Effective three-dimensional culture of hepatocyte-like cells generated from human adipose-derived mesenchymal stem cells.

Yu SaitoTetsuya IkemotoKazunori TokudaKatsuki MiyazakiShinichiro YamadaSatoru ImuraMasato MiyakeYuji MorineSeiichi OyadomariMitsuo Shimada

Published in: Journal of hepato-biliary-pancreatic sciences (2021)

Our new 3D culture protocol is effective to improve hepatocyte functions. Our HLCs might be promising for clinical cell transplantation to treat metabolic disease.

Keyphrases

mesenchymal stem cells
cell therapy
endothelial cells
liver injury
single cell
umbilical cord
randomized controlled trial
induced pluripotent stem cells
drug induced
bone marrow
pluripotent stem cells
stem cells