Effect of Bovine Milk Fat Globule Membrane and Lactoferrin in Infant Formula on Gut Microbiome and Metabolome at 4 Months of Age.

Maciej Chichlowski Nicholas A BokulichCheryl L HarrisJennifer L WamplerFei LiCarol Lynn BersethColin RudolphSteven S Wu

Published in: Current developments in nutrition (2021)

Addition of bovine MFGM and LF in infant formula was associated with subtle differences in stool microbiome and metabolome by 4 mo of age, including increased prevalence of Bacteroides species. Stool metabolite profiles may be consistent with altered microbial metabolism. This trial was registered at https://clinicaltrials.gov as NCT02274883.

Keyphrases

human milk
adipose tissue
clinical trial
risk factors
microbial community
phase iii
study protocol
phase ii
randomized controlled trial
fatty acid
preterm infants
low birth weight