There is a need for a factual understanding of the historical impact of pandemics in the world. Against this backdrop, this study provides a historical understanding of societal behaviour and responses to pandemics. Inferences are primarily drawn from a literature review from the past and present. The present analysis also reflects the ongoing COVID-19 pandemic in the world and India while providing a novel perspective to understand public health practices in a global context. It suggests the need for a more synchronised health response in pandemics while highlighting the uncertainties and challenges with historical evidence and comparisons to the ongoing pandemic. An emphasis is on learning from historical evidence and ascertaining how these retrospective diagnoses help make arguments about health and illness in our present moment.