A systematic review and meta-analysis of placebo effect in clinical trials on chronic prostatitis/chronic pelvic pain syndrome.

Andrey MorozovAndrey BazarkinDiana BabaevskayaMark TaratkinVasily KozlovAleksandr SuvorovLeonid SpivakJonathan McFarlandGiorgio I RussoDmitry V Enikeevnull null

Published in: The Prostate (2022)

Placebo significantly affected the subjective parameters (NIH-CPSI) and limitedly affected various other measurements of pain (visual analog scale, McGill pain questionnaire). There was no long-term effect on IPSS and objective measurements (Qmax, PVR). This study can be used in further clinical trials to develop general rules of CPPS treatment assessment.

Keyphrases

clinical trial
chronic pain
phase iii
neuropathic pain
double blind
randomized controlled trial
rectal cancer
cross sectional
open label
spinal cord injury
depressive symptoms
physical activity
sleep quality
replacement therapy