Severe COVID-19 in pregnancy has a distinct serum profile, including greater complement activation and dysregulation of serum lipids.

Marie AltendahlThalia MokChristine JangSeungjun YeoAustin QuachYalda Afshar

Published in: PloS one (2022)

Pregnancies with severe COVID-19 demonstrate greater inflammation and complement activation and dysregulation of serum lipids. This altered multiomic expression provides insight into the pathophysiology of severe COVID-19 in pregnancy and may serve as potential indicators for adverse pregnancy outcomes.

Keyphrases

pregnancy outcomes
coronavirus disease
sars cov

pregnant women
preterm birth
early onset

oxidative stress
poor prognosis

respiratory syndrome coronavirus
fatty acid