EVALUATION OF ACRYLATES/C10-30 ALKYL ACRYLATE CROSS- POLYMER MIXTURE EFFECTIVENESS ON O/W TYPE EMULSION FORMULATION.
Edita KizevicieneLaimute JonaitieneRimantas PeciuraPublished in: Acta poloniae pharmaceutica (2018)
Acrylates/C1O-30 alkyl acrylate cross-polymer mixtures were used in order to prepare stable and oil-in-water (o/w) pharmaceutical emulsions of organic oils. The resulting o/w pre-emulsions, prepared with different alkyl acrylate cross-polymers were unequally stable. We observed a synergistic effect when a polymer mixture was used and-the resulting pre-emulsions were more stable for significant duration. The observed effect is confirmed by, statistical analysis, the feature is remarkably important when we look for more stable pharmaceutical emulsions formed with less additives.