Can resveratrol modulate sirtuins in obesity and related diseases? A systematic review of randomized controlled trials.

Gabriela Macedo Fraiz Aline Rosignoli da Conceição Darlene Larissa de Souza Vilela Daniela Mayumi Usuda Prado Rocha Josefina Bressan Helen Hermana Miranda Hermsdorff

Published in: European journal of nutrition (2021)

Data from RCTs studies showed that RSV supplementation could stimulate SIRT-1 in humans, and therefore contribute to the treatment of excess weight and its comorbidities. However, more research is needed because it was not possible to confirm this effect truly. [PROSPERO registration number: CRD42020205571].

Keyphrases

weight loss
weight gain
metabolic syndrome
insulin resistance
type diabetes
body mass index
oxidative stress
big data
ischemia reperfusion injury
combination therapy
adipose tissue
respiratory tract
respiratory syncytial virus
machine learning
deep learning