Effect of adjuvant chemotherapy on localized dedifferentiated low-grade osteosarcoma: a systematic review.

Shinji TsukamotoA RighiA F MavrogenisT MasunagaK HonokiH FujiiA KidoY TanakaY TanakaC Errani

Published in: Musculoskeletal surgery (2024)

Results show a limited efficacy of adjuvant chemotherapy for localized dedifferentiated low-grade osteosarcoma. However, because this was a systematic review of retrospective studies that examined a small number of patients, future randomized controlled trials are needed.

Keyphrases

low grade
high grade
end stage renal disease
randomized controlled trial
ejection fraction
chronic kidney disease
newly diagnosed
prognostic factors
cross sectional
patient reported outcomes