Composite-derived monomers affect cell viability and cytokine expression in human leukocytes stimulated with Porphyromonas gingivalis.
Sheyla Omonte NevesLuísa Mourão Dias MagalhãesJôice Dias CorrêaWalderez Ornelas DutraKenneth John GollobTarcília Aparecida da SilvaMartinho Campolina Rebello HortaPaulo Eduardo Alencar SouzaPublished in: Journal of applied oral science : revista FOB (2019)
These results show that resin monomers are toxic to PBMC in a dose-dependent manner, and may influence the local immune inflammatory response and tissue damage mechanisms via regulation of bacterial-induced IL-1β and TNF-α secretion by PBMC.