Vagal Nerve Stimulation-Modulation of the Anti-Inflammatory Response and Clinical Outcome in Psoriatic Arthritis or Ankylosing Spondylitis.
Christina BrockS E RasmussenAnne Bech-DrewesHolger Jon MøllerBirgitte BrockBent Winding DeleuranAdam Donald FarmerMogens Pfeiffer JensenPublished in: Mediators of inflammation (2021)
This open-label study provides support for an anti-inflammatory effect of transcutaneous vagus nerve stimulation in patients with psoriatic arthritis and ankylosing spondylitis. The modulated immune response and reduced disease activity and CRP-levels raise the fascinating possibility of using neuromodulation as an add-on to existing pharmacological treatments.
Keyphrases
- ankylosing spondylitis
- disease activity
- rheumatoid arthritis
- systemic lupus erythematosus
- inflammatory response
- immune response
- rheumatoid arthritis patients
- open label
- anti inflammatory
- juvenile idiopathic arthritis
- clinical trial
- toll like receptor
- lipopolysaccharide induced
- radiation therapy
- randomized controlled trial
- lps induced
- squamous cell carcinoma
- phase ii
- phase ii study
- dendritic cells
- study protocol
- locally advanced