[Characteristics of lactobacteria strains, having diagnostic significance in gynecological practice.]

It has been shown that for most vaginal strains of Lactobacillus spp. characteristic variability of the duration of the adaptation period and the level of functional activity. In addition, only a small number of clinical strains produced lactic acid 24 hours after the start of cultivation. Therefore, to adequately assess the microecological status of the vaginal biotope, microscopic examination of both native material and cultures isolated on special nutrient media is not enough. It seems that, along with the use of modern methods of genetic analysis, the determination of in vitro growth characteristics, primarily lag-phase duration, and lactate production by lactic acid bacteria strains can clarify many issues related to the formation of dysbiotic states, in particular, in the vaginal biotope, and will also serve to increase the effectiveness of the prescribed treatment.