Compromised hippocampus-striatum pathway as a potential imaging biomarker of mild-traumatic brain injury and posttraumatic stress disorder.
D RangaprakashGopikrishna DeshpandeThomas A DanielAdam M GoodmanJennifer L RobinsonNouha SalibiJeffrey S KatzThomas S DenneyMichael N DretschPublished in: Human brain mapping (2017)
PTSD/mTBI are associated with hippocampal-striatal hyperconnectivity from which it is difficult to disengage, leading to a habit-like response toward episodic traumatic memories, which fits well with behavioral manifestations of combat-related PTSD/mTBI. Hum Brain Mapp 38:2843-2864, 2017. © 2017 The Authors Human Brain Mapping Published by Wiley Periodicals, Inc.
Keyphrases
- posttraumatic stress disorder
- mild traumatic brain injury
- cerebral ischemia
- high resolution
- resting state
- functional connectivity
- spinal cord injury
- prefrontal cortex
- subarachnoid hemorrhage
- brain injury
- parkinson disease
- blood brain barrier
- white matter
- high density
- cognitive impairment
- randomized controlled trial
- depressive symptoms
- human health
- meta analyses
- photodynamic therapy
- temporal lobe epilepsy
- drug induced
- deep brain stimulation