Comprehensive Observational and Longitudinal study on the Outbreak of Stroke-related Spasticity focusing on the Early Onset management with Botulinum NeuroToxin (COLOSSEO-BoNT): protocol for a real-world prospective observational study on upper limb spasticity.

Massimo MaranoAntonio SuppaMaria Giuseppina PalmieriEmanuela CecconiGiovanni FrisulloRoberta BovenziVittorio RisoAlexia AnziniMarianna BrienzaSabrina AnticoliDomenica CrupiMorena GiovannelliAndrea MassimianiSteno RinalduzziEmanuele MorenaMaria Carlotta MassaraLetizia CupiniFederica BressiFabio PilatoLoredana MaggiDonato SauchelliEnnio IezziDiego CentonzeIrene AprileVincenzo Di LazzaroDanilo ToniMaria Concetta Altavistanull null

Published in: BMJ open (2024)

NCT05379413.

Keyphrases

upper limb
early onset
late onset
atrial fibrillation
randomized controlled trial
cross sectional
spinal cord injury
botulinum toxin
blood brain barrier
brain injury