Characterization of the G protein-coupled receptor kinase 6 promoter reveals a functional CREB binding site.

Maike StegenAndrea EnglerCrista OchsenfarthIris MantheyJürgen PetersWinfried SiffertUlrich Hermann Frey

Published in: PloS one (2021)

We characterized the human GRK6 promoter and identified promoter activity to be influenced by a CREB binding site. PKC might be one determinant contributing to altered GRK6 expression.

Keyphrases

dna methylation
transcription factor
gene expression
endothelial cells
poor prognosis
protein kinase
induced pluripotent stem cells
tyrosine kinase
pluripotent stem cells
binding protein