Muscle MRI in a large cohort of patients with oculopharyngeal muscular dystrophy.
Alicia Alonso-JiménezRosemarie H M J M KroonAida Alejaldre-MonforteClaudia Nuñez-PeraltaCorinne G C HorlingsBaziel G M van EngelenMontse OlivéLaura GonzálezEnric Verges-GilCarmen ParadasCeledonio MárquezMatteo GaribaldiPía GallanoMaria José RodriguezLidia Gonzalez-QueredaCristina Dominguez GonzalezJohn VissingFreja FornanderAnne-Sofie Vibæk EisumTania García-SobrinoJulio PardoRoberto García-FigueirasNuria MuelasJuan Jesús VilchezSolange KapetanovicGiorgio TascaMauro MonforteEnzo RicciMaría Teresa GomezJorge Alfredo BevilacquaJorge Diaz-JaraIvonne Ingrid ZamoranoRobert Yves CarlierPascal LaforetAna Pelayo-NegroAlba Ramos-FransiAmaia MartínezChiara Marini-BettoloVolker StraubGerardo GutiérrezTanya StojkovicMaría Asunción MartínGermán MorísRoberto Fernández-TorrónAdolfo Lopez De MunaínElena Cortes-VicenteLuis Antonio Querol-GutiérrezRicardo Rojas-GarcíaIsabel IllaJordi Diaz-ManeraPublished in: Journal of neurology, neurosurgery, and psychiatry (2018)
We have described a pattern that can be considered characteristic of OPMD. An early combination of fat replacement in the tongue, adductor magnus and soleus can be helpful for differential diagnosis. The findings suggest the natural history of the disease from a radiological point of view. The information generated by this study is of high diagnostic value and important for clinical trial development.