Enhancing the expression and function of an EBV-TCR on engineered T cells by combining Sc-TCR design with CRISPR editing to prevent mispairing.

Shao-An XueYuan ChenRalf-Holger VossVirad KisanBo WangKe-Ke ChenFeng-Qin HeXiao-Xia ChengLaura ScolamieroAngelika HollerLiquan GaoEmma MorrisHans J Stauss

Published in: Cellular & molecular immunology (2020)

Keyphrases

crispr cas
genome editing
regulatory t cells
poor prognosis
epstein barr virus
diffuse large b cell lymphoma
genome wide
binding protein
dendritic cells
long non coding rna
gene expression