PDX Models in Theranostic Applications: Generation and Screening for B Cell Lymphoma of Human Origin.
Shayla ShmuelSébastien MonetteDina IbrahimPatricia M R PereiraPublished in: Molecular imaging and biology (2024)
This MIB guide briefly summarizes the generation of patient-derived xenografts (PDXs) and highlights the importance of validating PDX models for the presence of B cell lymphoma of human origin before their use in radiotheranostic applications. The use of this protocol will allow researchers to learn different methods for screening PDX models for Epstein-Barr virus (EBV)-infected B cell lymphoma.