Heterologous Expression of Human IFNγ and Anti-IL17 Antibody in Leishmania tarentolae Promastigote.

Arian Karimi RouzbahaniSeyedeh-Zeinab HosseiniMojgan BandehpourBahram KazemiAfsaneh TavasoliAmirreza Javadi MamaghaniFarnaz Kheirandish

Published in: Acta parasitologica (2024)

The effective achievement of producing a recombinant gene was done for the first time by replacing the I.L.L-CPC gene with plasmid pGH-hIFNγ-antiIL17 by targeted gene replacement. This cab can regulate the production of hIFNγ and anti-IL17. This makes it a viable choice for eliminating leishmania.

Keyphrases

copy number
genome wide
escherichia coli
poor prognosis

immune response
dendritic cells
crispr cas
gene expression

genome wide analysis
drug delivery
cell free

decision making
long non coding rna
pluripotent stem cells