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Assessment of flomoxef combined with amikacin in a hollow-fibre infection model for the treatment of neonatal sepsis in low- and middle-income healthcare settings.

Christopher A DarlowLaura McEnteeAdam JohnsonNicola FarringtonJennifer UnsworthAna Jimenez-ValverdeBhavana JagotaRuwanthi Kolamunnage-DonaRenata M A Da CostaSally EllisFrançois FranceschiMike SharlandMichael NeelyLaura J V PiddockShampa DasWilliam Hope
Published in: The Journal of antimicrobial chemotherapy (2022)
We conclude that the combination of flomoxef and amikacin is synergistic and is a potentially clinically effective regimen for the empirical treatment of neonatal sepsis in LMIC settings and is therefore suitable for further assessment in a clinical trial.
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