Laura J V Piddock (Laura Piddock, L J V Piddock)

ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 30

Top Venues

mBio

The Journal of antimicrobial chemotherapy

Nature communications

Nature reviews. Chemistry

University of Birmingham

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Birmingham Oct 01 2001

United Kingdom

Professor of Microbiology :: Immunity & Infection

Publications

Laura J V Piddock, Rohit Malpani, Alan Hennessy
Challenges and Opportunities with Antibiotic Discovery and Exploratory Research. ACS infectious diseases 10 (8) (2024)
Laura J V Piddock, Yewande Alimi, James Anderson, Damiano de Felice, Catrin E Moore, John-Arne Røttingen, Henry Skinner, Peter Beyer
Advancing global antibiotic research, development and access. Nature medicine (2024)
Laura J V Piddock, Rohit Malpani, Alan Hennessy
Challenges and Opportunities with Antibiotic Discovery and Exploratory Research. ACS infectious diseases (2024)
Biljana Kakaraskoska Boceska, Tuba Vilken, Xavier Basil Britto, Tomislav Kostyanev, Qiang Lin, Christine Lammens, Sally Ellis, Seamus O'Brien, Renata Maria Augusto da Costa, Aislinn Cook, Neal Russell, Julia Bielicki, Amy Riddell, Wolfgang Stohr, Ann Sarah Walker, Eitan Naaman Berezin, Emmanuel Roilides, Maia De Luca, Lorenza Romani, Daynia Ballot, Angela Dramowski, Jeannette Wadula, Sorasak Lochindarat, Suppawat Boonkasidecha, Flavia Namiiro, Hoang Thi Bich Ngoc, Minh Dien Tran, Tim R Cressey, Kanchana Preedisripipat, James Alexander Berkley, Robert Musyimi, Charalampos Zarras, Trusha Nana, Andrew C Whitelaw, Cely Barreto da Silva, Prenika Jaglal, Willy Ssengooba, Samir K Saha, Mohammad Shahidul Islam, Marisa Marcia Mussi-Pinhata, Cristina Gardonyi Carvalheiro, Laura J V Piddock, Paul T Heath, Surbhi Malhotra-Kumar, Michael Sharland, Youri Glupczynski, Herman Goossens
Assessment of three antibiotic combination regimens against Gram-negative bacteria causing neonatal sepsis in low- and middle-income countries. Nature communications 15 (1) (2024)
Biljana Kakaraskoska Boceska, Tuba Vilken, Xavier Basil Britto, Tomislav Kostyanev, Qiang Lin, Christine Lammens, Sally Ellis, Seamus O'Brien, Renata Maria Augusto da Costa, Aislinn Cook, Neal Russell, Julia Bielicki, Amy Riddell, Wolfgang Stohr, Ann Sarah Walker, Eitan Naaman Berezin, Emmanuel Roilides, Maia De Luca, Lorenza Romani, Daynia Ballot, Angela Dramowski, Jeannette Wadula, Sorasak Lochindarat, Suppawat Boonkasidecha, Flavia Namiiro, Hoang Thi Bich Ngoc, Minh Dien Tran, Tim R Cressey, Kanchana Preedisripipat, James Alexander Berkley, Robert Musyimi, Charalampos Zarras, Trusha Nana, Andrew C Whitelaw, Cely Barreto da Silva, Prenika Jaglal, Willy Ssengooba, Samir K Saha, Mohammad Shahidul Islam, Marisa Marcia Mussi-Pinhata, Cristina Gardonyi Carvalheiro, Laura J V Piddock, Paul T Heath, Surbhi Malhotra-Kumar, Michael Sharland, Youri Glupczynski, Herman Goossens
Assessment of three antibiotic combination regimens against Gram-negative bacteria causing neonatal sepsis in low- and middle-income countries. Nature communications 15 (1) (2024)
Vito Ricci, Jaswant Kaur, Jack Stone, Laura J V Piddock
Antibiotics do not induce expression of acrAB directly but via a RamA-dependent pathway. Antimicrobial agents and chemotherapy (2023)
Alasdair P MacGowan, M L G Attwood, Alan R Noel, Ross W Barber, Zachary Aron, Timothy J Opperman, Elizabeth Grimsey, Jack Stone, Vito Ricci, Laura J V Piddock
Exposure of Escherichia coli to antibiotic-efflux pump inhibitor combinations in a pharmacokinetic model: impact on bacterial clearance and drug resistance. The Journal of antimicrobial chemotherapy (2023)
Ursula Theuretzbacher, Benjamin Blasco, Maëlle Duffey, Laura J V Piddock
Unrealized targets in the discovery of antibiotics for Gram-negative bacterial infections. Nature reviews. Drug discovery (2023)
Laura J V Piddock
BSAC Vanguard Report Series: The future of drug development. The Journal of antimicrobial chemotherapy 77 (3) (2022)
Christopher A Darlow, Laura McEntee, Adam Johnson, Nicola Farrington, Jennifer Unsworth, Ana Jimenez-Valverde, Bhavana Jagota, Ruwanthi Kolamunnage-Dona, Renata M A Da Costa, Sally Ellis, François Franceschi, Mike Sharland, Michael Neely, Laura J V Piddock, Shampa Das, William Hope
Assessment of flomoxef combined with amikacin in a hollow-fibre infection model for the treatment of neonatal sepsis in low- and middle-income healthcare settings. The Journal of antimicrobial chemotherapy 77 (12) (2022)
Maria Laura Ciusa, Robert L Marshall, Vito Ricci, Jack W Stone, Laura J V Piddock
Absence, loss-of-function, or inhibition of Escherichia coli AcrB does not increase expression of other efflux pump genes supporting the discovery of AcrB inhibitors as antibiotic adjuvants. The Journal of antimicrobial chemotherapy 77 (3) (2022)
Christopher A Darlow, Nicola Farrington, Adam Johnson, Laura McEntee, Jennifer Unsworth, Ana Jimenez-Valverde, Ruwanthi Kolamunnage-Dona, Renata M A Da Costa, Sally Ellis, François Franceschi, Mike Sharland, Michael Neely, Laura J V Piddock, Shampa Das, William Hope
Flomoxef and fosfomycin in combination for the treatment of neonatal sepsis in the setting of highly prevalent antimicrobial resistance. The Journal of antimicrobial chemotherapy 77 (5) (2022)
Jessica M A Blair, Pauline Siasat, Helen E McNeil, Abigail Colclough, Vito Ricci, Amelia J Lawler, Hind Abdalaal, Michelle M C Buckner, Alison Baylay, Stephen J W Busby, Laura J V Piddock
EnvR is a potent repressor of acrAB transcription in Salmonella. The Journal of antimicrobial chemotherapy (2022)
Marcus Miethke, Marco Pieroni, Tilmann Weber, Mark Brönstrup, Peter Hammann, Ludovic Halby, Paola B Arimondo, Philippe Glaser, Bertrand Aigle, Helge B Bode, Rui Moreira, Yanyan Li, Andriy Luzhetskyy, Marnix H Medema, Jean-Luc Pernodet, Marc Stadler, José Rubén Tormo, Olga Genilloud, Andrew W Truman, Kira J Weissman, Eriko Takano, Stefano Sabatini, Evi Stegmann, Heike Brötz-Oesterhelt, Wolfgang Wohlleben, Myriam Seemann, Martin Empting, Anna K H Hirsch, Brigitta Loretz, Claus-Michael Lehr, Alexander Titz, Jennifer Herrmann, Timo Jaeger, Silke Alt, Thomas Hesterkamp, Mathias Winterhalter, Andrea Schiefer, Kenneth M Pfarr, Achim Hoerauf, Heather Graz, Michael Graz, Mika Lindvall, Savithri Ramurthy, Anders Karlén, Maarten van Dongen, Hrvoje Petkovic, Andreas Keller, Frédéric Peyrane, Stefano Donadio, Laurent Fraisse, Laura J V Piddock, Ian H Gilbert, Heinz E Moser, Daniel Krug
Towards the sustainable discovery and development of new antibiotics. Nature reviews. Chemistry 5 (10) (2021)
Xuan Wang-Kan, Giovanny Rodríguez-Blanco, Andrew D Southam, Catherine L Winder, Warwick B Dunn, Alasdair Ivens, Laura J V Piddock
Metabolomics Reveal Potential Natural Substrates of AcrB in Escherichia coli and Salmonella enterica Serovar Typhimurium. mBio 12 (2) (2021)
Marcus Miethke, Marco Pieroni, Tilmann Weber, Mark Brönstrup, Peter Hammann, Ludovic Halby, Paola B Arimondo, Philippe Glaser, Bertrand Aigle, Helge B Bode, Rui Moreira, Yanyan Li, Andriy Luzhetskyy, Marnix H Medema, Jean-Luc Pernodet, Marc Stadler, José Rubén Tormo, Olga Genilloud, Andrew W Truman, Kira J Weissman, Eriko Takano, Stefano Sabatini, Evi Stegmann, Heike Brötz-Oesterhelt, Wolfgang Wohlleben, Myriam Seemann, Martin Empting, Anna K H Hirsch, Brigitta Loretz, Claus-Michael Lehr, Alexander Titz, Jennifer Herrmann, Timo Jaeger, Silke Alt, Thomas Hesterkamp, Mathias Winterhalter, Andrea Schiefer, Kenneth M Pfarr, Achim Hoerauf, Heather Graz, Michael Graz, Mika Lindvall, Savithri Ramurthy, Anders Karlén, Maarten van Dongen, Hrvoje Petkovic, Andreas Keller, Frédéric Peyrane, Stefano Donadio, Laurent Fraisse, Laura J V Piddock, Ian H Gilbert, Heinz E Moser, Daniel Krug
Towards the sustainable discovery and development of new antibiotics. Nature reviews. Chemistry 5 (10) (2021)
Marcus Miethke, Marco Pieroni, Tilmann Weber, Mark Brönstrup, Peter Hammann, Ludovic Halby, Paola B Arimondo, Philippe Glaser, Bertrand Aigle, Helge B Bode, Rui Moreira, Yanyan Li, Andriy Luzhetskyy, Marnix H Medema, Jean-Luc Pernodet, Marc Stadler, José Rubén Tormo, Olga Genilloud, Andrew W Truman, Kira J Weissman, Eriko Takano, Stefano Sabatini, Evi Stegmann, Heike Brötz-Oesterhelt, Wolfgang Wohlleben, Myriam Seemann, Martin Empting, Anna K H Hirsch, Brigitta Loretz, Claus-Michael Lehr, Alexander Titz, Jennifer Herrmann, Timo Jaeger, Silke Alt, Thomas Hesterkamp, Mathias Winterhalter, Andrea Schiefer, Kenneth M Pfarr, Achim Hoerauf, Heather Graz, Michael Graz, Mika Lindvall, Savithri Ramurthy, Anders Karlén, Maarten van Dongen, Hrvoje Petkovic, Andreas Keller, Frédéric Peyrane, Stefano Donadio, Laurent Fraisse, Laura J V Piddock, Ian H Gilbert, Heinz E Moser, Daniel Krug
Towards the sustainable discovery and development of new antibiotics. Nature reviews. Chemistry (2021)
Elizabeth M Grimsey, Natasha Weston, Vito Ricci, Jack W Stone, Laura J V Piddock
Overexpression of RamA, Which Regulates Production of the Multidrug Resistance Efflux Pump AcrAB-TolC, Increases Mutation Rate and Influences Drug Resistance Phenotype. Antimicrobial agents and chemotherapy 64 (4) (2020)
Eamonn Reading, Zainab Ahdash, Chiara Fais, Vito Ricci, Xuan Wang-Kan, Elizabeth Grimsey, Jack Stone, Giuliano Malloci, Andy M Lau, Heather Findlay, Albert Konijnenberg, Paula J Booth, Paolo Ruggerone, Attilio Vittorio Vargiu, Laura J V Piddock, Argyris Politis
Perturbed structural dynamics underlie inhibition and altered efflux of the multidrug resistance pump AcrB. Nature communications 11 (1) (2020)
Vito Ricci, Dexian Zhang, Christopher Teale, Laura J V Piddock
The O-Antigen Epitope Governs Susceptibility to Colistin in Salmonella enterica. mBio 11 (1) (2020)
Robert L Marshall, Georgina S Lloyd, Amelia J Lawler, Sarah J Element, Jaswant Kaur, Maria Laura Ciusa, Vito Ricci, Andreas Tschumi, Holger Kühne, Luke J Alderwick, Laura J V Piddock
New Multidrug Efflux Inhibitors for Gram-Negative Bacteria. mBio 11 (4) (2020)
Elizabeth M Grimsey, Chiara Fais, Robert L Marshall, Vito Ricci, Maria Laura Ciusa, Jack W Stone, Alasdair Ivens, Giuliano Malloci, Paolo Ruggerone, Attilio Vittorio Vargiu, Laura J V Piddock
Chlorpromazine and Amitriptyline Are Substrates and Inhibitors of the AcrB Multidrug Efflux Pump. mBio 11 (3) (2020)
Michelle M C Buckner, M Laura Ciusa, Richard W Meek, Alice R Moorey, Gregory E McCallum, Emma L Prentice, Jeremy P Reid, Luke J Alderwick, Alessandro Di Maio, Laura J V Piddock
HIV Drugs Inhibit Transfer of Plasmids Carrying Extended-Spectrum β-Lactamase and Carbapenemase Genes. mBio 11 (1) (2020)
Elizabeth K Benedikz, Dalan Bailey, Charlotte N L Cook, Daniel Gonçalves-Carneiro, Michelle M C Buckner, Jessica M A Blair, Timothy J Wells, Nicola F Fletcher, Margaret Goodall, Adriana Flores-Langarica, Robert A Kingsley, Jens Madsen, Jessica L Teeling, L Sebastian Johnston, Calman A MacLennan, Peter Balfe, Ian R Henderson, Laura J V Piddock, Adam F Cunningham, Jane A McKeating
Bacterial flagellin promotes viral entry via an NF-kB and Toll Like Receptor 5 dependent pathway. Scientific reports 9 (1) (2019)
Dijun Du, Xuan Wang-Kan, Arthur Neuberger, Hendrik W van Veen, Klaas M Pos, Laura J V Piddock, Ben F Luisi
Multidrug efflux pumps: structure, function and regulation. Nature reviews. Microbiology 16 (9) (2019)
Michelle M C Buckner, Howard T H Saw, Rachael N Osagie, Alan McNally, Vito Ricci, Matthew E Wand, Neil Woodford, Alasdair Ivens, Mark A Webber, Laura J V Piddock
Clinically Relevant Plasmid-Host Interactions Indicate that Transcriptional and Not Genomic Modifications Ameliorate Fitness Costs of Klebsiella pneumoniae Carbapenemase-Carrying Plasmids. mBio 9 (2) (2018)
Edward R Bevan, Alan McNally, Christopher M Thomas, Laura J V Piddock, Peter M Hawkey
Acquisition and Loss of CTX-M-Producing and Non-Producing Escherichia coli in the Fecal Microbiome of Travelers to South Asia. mBio 9 (6) (2018)
Xuan Wang-Kan, Jessica M A Blair, Barbara Chirullo, Jonathan Betts, Roberto M La Ragione, Alasdair Ivens, Vito Ricci, Timothy J Opperman, Laura J V Piddock
Lack of AcrB Efflux Function Confers Loss of Virulence on Salmonella enterica Serovar Typhimurium. mBio 8 (4) (2017)
Prateek Sharma, James R J Haycocks, Alistair D Middlemiss, Rachel A Kettles, Laura E Sellars, Vito Ricci, Laura J V Piddock, David C Grainger
The multiple antibiotic resistance operon of enteric bacteria controls DNA repair and outer membrane integrity. Nature communications 8 (1) (2017)
Michelle M C Buckner, Jessica M A Blair, Roberto M La Ragione, Jane Newcombe, Daniel J Dwyer, Alasdair Ivens, Laura J V Piddock
Beyond Antimicrobial Resistance: Evidence for a Distinct Role of the AcrD Efflux Pump in Salmonella Biology. mBio 7 (6) (2016)

Laura J V Piddock.css-eqlu8i{font-size:small;padding-left:4px;} (Laura Piddock, L J V Piddock)

Publication Activity (10 Years)

Top Topics

Top Venues

Laura J V Piddock (Laura Piddock, L J V Piddock)