Extracellular vesicles as potential tools for regenerative therapy.
Jose Antonio Rodriguez-NavarroJorge Pascual-GuerraSilvia SacristanMaria Del Carmen NogalesJuan Antonio Fafián-LaboraAna O'LoghlenPublished in: Molecular & cellular oncology (2020)
Small extracellular vesicles released by fibroblasts from young human donors diminish lipid peroxidation in senescent cells and in different old mice organs due to their enrichment in Glutathione-S-transferase Mu lipid antioxidant activity.
Keyphrases
- induced apoptosis
- endothelial cells
- stem cells
- cell cycle arrest
- fatty acid
- cell therapy
- mesenchymal stem cells
- high fat diet induced
- pluripotent stem cells
- endoplasmic reticulum stress
- extracellular matrix
- oxidative stress
- type diabetes
- metabolic syndrome
- kidney transplantation
- human health
- bone marrow
- adipose tissue
- pi k akt