The Prognostic Role of Mismatch Repair Status and CDX-2 Expression with Inflammatory Markers and Pathological Risk Factors in Stage II and III Colon Cancer: Multicenter Real-Life Data.

Sabin Göktas AydinOmer Fatih OlmezOguzhan SelviCaglayan GeredeliFerhat OzdenAhmet BiliciOzgur AcikgozEbru KarciYasin KutluJamshid HamdardAhmet Aydin

Published in: Journal of gastrointestinal cancer (2023)

CDX-2 loss was an independent prognostic factor for DFS and disease recurrence in early-stage colon cancer. MSS patients with CDX-2 loss had significantly worse survival outcomes, and this might be the reason for deciding on adjuvant chemotherapy.

Keyphrases

prognostic factors
early stage
risk factors
poor prognosis
big data
cross sectional
binding protein
double blind
long non coding rna
lymph node
radiation therapy
data analysis
rectal cancer