Trimethoprim/sulfamethoxazole for nocardiosis in solid organ transplant recipients: Real-life data from a multicentre retrospective study.

Pierre-Louis ConanMarie MatignonAlexandre BleibtreuHélène GuillotSteven Van LaeckeHenri BrenierRomain CrochetteGiovanna Melica Mario Fernández-RuizJacques DantalLaura N WaltiCharlène LeviCécile ChauvetJulien De GreefSierk D MarbusNicolas J MuellerMargareta IevenFanny VuottoOlivier LortholaryJulien CoussementDavid Lebeaux

Published in: Transplant infectious disease : an official journal of the Transplantation Society (2021)

TMP-SMX monotherapy appears to be effective for the treatment of most nocardiosis among SOT recipients. Interventional studies are needed to compare its safety and effectiveness with those of other regimens used to treat posttransplant nocardiosis.

Keyphrases

combination therapy
randomized controlled trial
systematic review
clinical trial
electronic health record
big data
open label
cross sectional
machine learning
case control
artificial intelligence
microbial community
wastewater treatment