Non-operative management after chemoradiotherapy plus consolidation or sandwich (induction with bevacizumab and consolidation) chemotherapy in patients with locally advanced rectal cancer: a multicentre, randomised phase II trial (NOMINATE trial).

Takashi AkiyoshiEiji ShinozakiSenzo TaguchiAkiko ChinoMakiko HiratsukaTetsuro TominagaTakashi NonakaShigeo TodaShuichiro MatobaShimpei MatsuiKoji OkabayashiToshiki MukaiYukiharu HiyoshiTomohiro YamaguchiToshiya NagasakiKensei YamaguchiMasashi UenoHiroya KuroyanagiYosuke FukunagaNaoki IshizukaTsuyoshi Konishinull null

Published in: BMJ open (2022)

jRCTs051200121.

Keyphrases

locally advanced
rectal cancer
study protocol
clinical trial
open label
phase iii
placebo controlled
double blind
neoadjuvant chemotherapy
phase ii
phase ii study
randomized controlled trial
squamous cell carcinoma
radiation therapy
metastatic colorectal cancer
cross sectional
lymph node