Cytokine-directed cellular cross-talk imprints synovial pathotypes in rheumatoid arthritis.
Maximilian KuglerMirjam DellingerFelix KartnigLena MüllerTeresa PreglejLeonhard X HeinzElisabeth SimaderLisa GöschlStephan E PuchnerSebastian WeissLisa E ShawMatthias FarlikWolfgang WeningerGiulio Superti-FurgaJosef S SmolenGuenter SteinerDaniel AletahaHans P KienerMyles J LewisCostantino PitzalisAnela TosevskaThomas KaronitschMichael Markus BonelliPublished in: Annals of the rheumatic diseases (2023)
Our study highlights the role of cytokine-activated FLS in orchestrating inflammation-associated synovial pathotypes providing novel insights into disease mechanisms of RA.