Costantino Pitzalis (C Pitzalis)

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 68

Top Venues

Annals of the rheumatic diseases

Nature communications

Arthritis & rheumatology (Hoboken, N.J.)

Journal of immunology (Baltimore, Md. : 1950)

Queen Mary University of London

University of London (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Queen Mary University of London May 01 2007

United Kingdom

Head of Centre/Honorary Consultant Rheumatologist :: Centre for Experimental Medicine & Rheumatology

King's College London

United Kingdom

Professor of Experimental Rheumatology/Honorary Consultant in Rheumatology :: Rheumatology

King's College London

United Kingdom

Wellcome Trust Senior Lecturer/Honorary Consultant in Rheumatology :: Rheumatology

Guy's Hospital

United Kingdom

Lecturer/Honorary Senior Registrar in Rheumatology :: Rheumatology

Guy's and Saint Thomas' NHS Foundation Trust

United Kingdom

Registrar in General Medicine

Education History

University of London

United Kingdom

PHD

Publications

Alessandra Nerviani, Marie-Astrid Boutet, Giulia Maria Ghirardi, Katriona Goldmann, Elisabetta Sciacca, Felice Rivellese, Elena Pontarini, Edoardo Prediletto, Federico Abatecola, Mattia Caliste, Sara Pagani, Daniele Mauro, Mattia Bellan, Cankut Cubuk, Rachel Lau, Sarah E Church, Briana M Hudson, Frances Humby, Michele Bombardieri, Myles J Lewis, Costantino Pitzalis
Axl and MerTK regulate synovial inflammation and are modulated by IL-6 inhibition in rheumatoid arthritis. Nature communications 15 (1) (2024)
Alessandra Nerviani, Marie-Astrid Boutet, Giulia Maria Ghirardi, Katriona Goldmann, Elisabetta Sciacca, Felice Rivellese, Elena Pontarini, Edoardo Prediletto, Federico Abatecola, Mattia Caliste, Sara Pagani, Daniele Mauro, Mattia Bellan, Cankut Cubuk, Rachel Lau, Sarah E Church, Briana M Hudson, Frances Humby, Michele Bombardieri, Myles J Lewis, Costantino Pitzalis
Axl and MerTK regulate synovial inflammation and are modulated by IL-6 inhibition in rheumatoid arthritis. Nature communications 15 (1) (2024)
Zilong Bai, Nicholas Bartelo, Maryam Aslam, Elisabeth A Murphy, Caryn R Hale, Nathalie E Blachere, Salina Parveen, Edoardo Spolaore, Edward F DiCarlo, Ellen M Gravallese, Melanie H Smith, null null, Mayu O Frank, Caroline S Jiang, Haotan Zhang, Christina Pyrgaki, Myles J Lewis, Shafaq Sikandar, Costantino Pitzalis, Joseph B Lesnak, Khadijah Mazhar, Theodore John Price, Anne-Marie Malfait, Rachel E Miller, Fan Zhang, Susan M Goodman, Robert B Darnell, Fei Wang, Dana E Orange
Synovial fibroblast gene expression is associated with sensory nerve growth and pain in rheumatoid arthritis. Science translational medicine 16 (742) (2024)
James Perera, Chiara Aurora Delrosso, Alessandra Nerviani, Costantino Pitzalis
Clinical Phenotypes, Serological Biomarkers, and Synovial Features Defining Seropositive and Seronegative Rheumatoid Arthritis: A Literature Review. Cells 13 (9) (2024)
Garrett S Dunlap, Aaron Wagner, Nida Meednu, Ruoqiao Huiyi Wang, Fan Zhang, Jabea Cyril Ekabe, Anna Helena Jonsson, Kevin Wei, Saori Sakaue, Aparna Nathan, null null, Vivian P Bykerk, Laura T Donlin, Susan M Goodman, Gary S Firestein, David L Boyle, V Michael Holers, Larry W Moreland, Darren Tabechian, Costantino Pitzalis, Andrew Filer, Soumya Raychaudhuri, Michael B Brenner, Juilee Thakar, Andrew McDavid, Deepak A Rao, Jennifer H Anolik
Clonal associations between lymphocyte subsets and functional states in rheumatoid arthritis synovium. Nature communications 15 (1) (2024)
Stephanie R Zack, Osama Alzoubi, Neha Satoeya, Kunwar P Singh, Sania Deen, Wes Nijim, Myles J Lewis, Costantino Pitzalis, Nadera Sweiss, Lionel B Ivashkiv, Shiva Shahrara
ANOTHER NOTCH IN THE BELT OF RHEUMATOID ARTHRITIS. Arthritis & rheumatology (Hoboken, N.J.) (2024)
Garrett S Dunlap, Aaron Wagner, Nida Meednu, Ruoqiao Huiyi Wang, Fan Zhang, Jabea Cyril Ekabe, Anna Helena Jonsson, Kevin Wei, Saori Sakaue, Aparna Nathan, null null, Vivian P Bykerk, Laura T Donlin, Susan M Goodman, Gary S Firestein, David L Boyle, V Michael Holers, Larry W Moreland, Darren Tabechian, Costantino Pitzalis, Andrew Filer, Soumya Raychaudhuri, Michael B Brenner, Juilee Thakar, Andrew McDavid, Deepak A Rao, Jennifer H Anolik
Clonal associations between lymphocyte subsets and functional states in rheumatoid arthritis synovium. Nature communications 15 (1) (2024)
Garrett S Dunlap, Aaron Wagner, Nida Meednu, Ruoqiao Huiyi Wang, Fan Zhang, Jabea Cyril Ekabe, Anna Helena Jonsson, Kevin Wei, Saori Sakaue, Aparna Nathan, null null, Vivian P Bykerk, Laura T Donlin, Susan M Goodman, Gary S Firestein, David L Boyle, V Michael Holers, Larry W Moreland, Darren Tabechian, Costantino Pitzalis, Andrew Filer, Soumya Raychaudhuri, Michael B Brenner, Juilee Thakar, Andrew McDavid, Deepak A Rao, Jennifer H Anolik
Clonal associations between lymphocyte subsets and functional states in rheumatoid arthritis synovium. Nature communications 15 (1) (2024)
Zilong Bai, Nicholas Bartelo, Maryam Aslam, Elisabeth A Murphy, Caryn R Hale, Nathalie E Blachere, Salina Parveen, Edoardo Spolaore, Edward F DiCarlo, Ellen M Gravallese, Melanie H Smith, null null, Mayu O Frank, Caroline S Jiang, Haotan Zhang, Christina Pyrgaki, Myles J Lewis, Shafaq Sikandar, Costantino Pitzalis, Joseph B Lesnak, Khadijah Mazhar, Theodore John Price, Anne-Marie Malfait, Rachel E Miller, Fan Zhang, Susan M Goodman, Robert B Darnell, Fei Wang, Dana E Orange
Synovial fibroblast gene expression is associated with sensory nerve growth and pain in rheumatoid arthritis. Science translational medicine 16 (742) (2024)
Bethan L Thomas, Trinidad Montero-Melendez, Silvia Oggero, Magdalena K Kaneva, David Chambers, Andreia L Pinto, Alessandra Nerviani, Davide Lucchesi, Shani Austin-Williams, Mohammed T Hussain, Costantino Pitzalis, Benjamin Allen, Marzia Malcangio, Francesco Dell'Accio, Lucy Victoria Norling, Mauro Perretti
Molecular Determinants of Neutrophil Extracellular Vesicles That Drive Cartilage Regeneration in Inflammatory Arthritis. Arthritis & rheumatology (Hoboken, N.J.) (2024)
Alessandra Nerviani, Marie-Astrid Boutet, Giulia Maria Ghirardi, Katriona Goldmann, Elisabetta Sciacca, Felice Rivellese, Elena Pontarini, Edoardo Prediletto, Federico Abatecola, Mattia Caliste, Sara Pagani, Daniele Mauro, Mattia Bellan, Cankut Cubuk, Rachel Lau, Sarah E Church, Briana M Hudson, Frances Humby, Michele Bombardieri, Myles J Lewis, Costantino Pitzalis
Axl and MerTK regulate synovial inflammation and are modulated by IL-6 inhibition in rheumatoid arthritis. Nature communications 15 (1) (2024)
Garrett S Dunlap, Aaron Wagner, Nida Meednu, Ruoqiao Huiyi Wang, Fan Zhang, Jabea Cyril Ekabe, Anna Helena Jonsson, Kevin Wei, Saori Sakaue, Aparna Nathan, null null, Vivian P Bykerk, Laura T Donlin, Susan M Goodman, Gary S Firestein, David L Boyle, V Michael Holers, Larry W Moreland, Darren Tabechian, Costantino Pitzalis, Andrew Filer, Soumya Raychaudhuri, Michael B Brenner, Juilee Thakar, Andrew McDavid, Deepak A Rao, Jennifer H Anolik
Clonal associations between lymphocyte subsets and functional states in rheumatoid arthritis synovium. Nature communications 15 (1) (2024)
Bethan L Thomas, Trinidad Montero-Melendez, Silvia Oggero, Magdalena K Kaneva, David Chambers, Andreia L Pinto, Alessandra Nerviani, Davide Lucchesi, Shani Austin-Williams, Mohammed T Hussain, Costantino Pitzalis, Benjamin Allen, Marzia Malcangio, Francesco Dell'Accio, Lucy Victoria Norling, Mauro Perretti
Molecular determinants of neutrophil extracellular vesicles that drive cartilage regeneration in inflammatory arthritis. Arthritis & rheumatology (Hoboken, N.J.) (2024)
Zilong Bai, Nicholas Bartelo, Maryam Aslam, Elisabeth A Murphy, Caryn R Hale, Nathalie E Blachere, Salina Parveen, Edoardo Spolaore, Edward F DiCarlo, Ellen M Gravallese, Melanie H Smith, null null, Mayu O Frank, Caroline S Jiang, Haotan Zhang, Christina Pyrgaki, Myles J Lewis, Shafaq Sikandar, Costantino Pitzalis, Joseph B Lesnak, Khadijah Mazhar, Theodore John Price, Anne-Marie Malfait, Rachel E Miller, Fan Zhang, Susan M Goodman, Robert B Darnell, Fei Wang, Dana E Orange
Synovial fibroblast gene expression is associated with sensory nerve growth and pain in rheumatoid arthritis. Science translational medicine 16 (742) (2024)
Alessandra Nerviani, Marie-Astrid Boutet, Giulia Maria Ghirardi, Katriona Goldmann, Elisabetta Sciacca, Felice Rivellese, Elena Pontarini, Edoardo Prediletto, Federico Abatecola, Mattia Caliste, Sara Pagani, Daniele Mauro, Mattia Bellan, Cankut Cubuk, Rachel Lau, Sarah E Church, Briana M Hudson, Frances Humby, Michele Bombardieri, Myles J Lewis, Costantino Pitzalis
Axl and MerTK regulate synovial inflammation and are modulated by IL-6 inhibition in rheumatoid arthritis. Nature communications 15 (1) (2024)
Stephanie R Zack, Osama Alzoubi, Neha Satoeya, Kunwar P Singh, Sania Deen, Wes Nijim, Myles J Lewis, Costantino Pitzalis, Nadera Sweiss, Lionel B Ivashkiv, Shiva Shahrara
Another Notch in the Belt of Rheumatoid Arthritis. Arthritis & rheumatology (Hoboken, N.J.) (2024)
Zilong Bai, Nicholas Bartelo, Maryam Aslam, Elisabeth A Murphy, Caryn R Hale, Nathalie E Blachere, Salina Parveen, Edoardo Spolaore, Edward F DiCarlo, Ellen M Gravallese, Melanie H Smith, null null, Mayu O Frank, Caroline S Jiang, Haotan Zhang, Christina Pyrgaki, Myles J Lewis, Shafaq Sikandar, Costantino Pitzalis, Joseph B Lesnak, Khadijah Mazhar, Theodore John Price, Anne-Marie Malfait, Rachel E Miller, Fan Zhang, Susan M Goodman, Robert B Darnell, Fei Wang, Dana E Orange
Synovial fibroblast gene expression is associated with sensory nerve growth and pain in rheumatoid arthritis. Science translational medicine 16 (742) (2024)
Garrett S Dunlap, Aaron Wagner, Nida Meednu, Ruoqiao Huiyi Wang, Fan Zhang, Jabea Cyril Ekabe, Anna Helena Jonsson, Kevin Wei, Saori Sakaue, Aparna Nathan, null null, Vivian P Bykerk, Laura T Donlin, Susan M Goodman, Gary S Firestein, David L Boyle, V Michael Holers, Larry W Moreland, Darren Tabechian, Costantino Pitzalis, Andrew Filer, Soumya Raychaudhuri, Michael B Brenner, Juilee Thakar, Andrew McDavid, Deepak A Rao, Jennifer H Anolik
Clonal associations between lymphocyte subsets and functional states in rheumatoid arthritis synovium. Nature communications 15 (1) (2024)
James Perera, Chiara Aurora Delrosso, Alessandra Nerviani, Costantino Pitzalis
Clinical Phenotypes, Serological Biomarkers, and Synovial Features Defining Seropositive and Seronegative Rheumatoid Arthritis: A Literature Review. Cells 13 (9) (2024)
Garrett S Dunlap, Aaron Wagner, Nida Meednu, Ruoqiao Huiyi Wang, Fan Zhang, Jabea Cyril Ekabe, Anna Helena Jonsson, Kevin Wei, Saori Sakaue, Aparna Nathan, null null, Vivian P Bykerk, Laura T Donlin, Susan M Goodman, Gary S Firestein, David L Boyle, V Michael Holers, Larry W Moreland, Darren Tabechian, Costantino Pitzalis, Andrew Filer, Soumya Raychaudhuri, Michael B Brenner, Juilee Thakar, Andrew McDavid, Deepak A Rao, Jennifer H Anolik
Clonal associations between lymphocyte subsets and functional states in rheumatoid arthritis synovium. Nature communications 15 (1) (2024)
James Perera, Chiara Aurora Delrosso, Alessandra Nerviani, Costantino Pitzalis
Clinical Phenotypes, Serological Biomarkers, and Synovial Features Defining Seropositive and Seronegative Rheumatoid Arthritis: A Literature Review. Cells 13 (9) (2024)
Zilong Bai, Nicholas Bartelo, Maryam Aslam, Elisabeth A Murphy, Caryn R Hale, Nathalie E Blachere, Salina Parveen, Edoardo Spolaore, Edward F DiCarlo, Ellen M Gravallese, Melanie H Smith, null null, Mayu O Frank, Caroline S Jiang, Haotan Zhang, Christina Pyrgaki, Myles J Lewis, Shafaq Sikandar, Costantino Pitzalis, Joseph B Lesnak, Khadijah Mazhar, Theodore John Price, Anne-Marie Malfait, Rachel E Miller, Fan Zhang, Susan M Goodman, Robert B Darnell, Fei Wang, Dana E Orange
Synovial fibroblast gene expression is associated with sensory nerve growth and pain in rheumatoid arthritis. Science translational medicine 16 (742) (2024)
Katriona Goldmann, Athina Spiliopoulou, Andrii Iakovliev, Darren Plant, Nisha Nair, Cankut Cubuk, null null, Paul M McKeigue, Michael R Barnes, Richard B Warren, Costantino Pitzalis, Myles J Lewis
Expression quantitative trait loci analysis in rheumatoid arthritis identifies tissue specific variants associated with severity and outcome. Annals of the rheumatic diseases (2023)
Anja Meyer, Ryan E Sienes, Wes Nijim, Brian Zanotti, Sadiq Umar, Michael V Volin, Katrien Van Raemdonck, Myles J Lewis, Costantino Pitzalis, Shiva Arami, Mina Al-Awqati, Huan J Chang, Pim Jetanalin, Larissa Valor-Méndez, Nadera Sweiss, Shiva Shahrara
Syntenin-1-mediated arthritogenicity is advanced by reprogramming RA metabolic macrophages and Th1 cells. Annals of the rheumatic diseases (2023)
Anja Meyer, Ryan E Sienes, Wes Nijim, Brian Zanotti, Sadiq Umar, Michael V Volin, Katrien Van Raemdonck, Myles J Lewis, Costantino Pitzalis, Shiva Arami, Mina Al-Awqati, Huan J Chang, Pim Jetanalin, Larissa Valor-Méndez, Nadera Sweiss, Shiva Shahrara
Syntenin-1-mediated arthritogenicity is advanced by reprogramming RA metabolic macrophages and Th1 cells. Annals of the rheumatic diseases (2023)
Maximilian Kugler, Mirjam Dellinger, Felix Kartnig, Lena Müller, Teresa Preglej, Leonhard X Heinz, Elisabeth Simader, Lisa Göschl, Stephan E Puchner, Sebastian Weiss, Lisa E Shaw, Matthias Farlik, Wolfgang Weninger, Giulio Superti-Furga, Josef S Smolen, Guenter Steiner, Daniel Aletaha, Hans P Kiener, Myles J Lewis, Costantino Pitzalis, Anela Tosevska, Thomas Karonitsch, Michael Markus Bonelli
Cytokine-directed cellular cross-talk imprints synovial pathotypes in rheumatoid arthritis. Annals of the rheumatic diseases (2023)
Susan Siyu Wang, Myles J Lewis, Costantino Pitzalis
DNA Methylation Signatures of Response to Conventional Synthetic and Biologic Disease-Modifying Antirheumatic Drugs (DMARDs) in Rheumatoid Arthritis. Biomedicines 11 (7) (2023)
Anja Meyer, Ryan E Sienes, Wes Nijim, Brian Zanotti, Sadiq Umar, Michael V Volin, Katrien Van Raemdonck, Myles J Lewis, Costantino Pitzalis, Shiva Arami, Mina Al-Awqati, Huan J Chang, Pim Jetanalin, Larissa Valor-Méndez, Nadera Sweiss, Shiva Shahrara
Syntenin-1-mediated arthritogenicity is advanced by reprogramming RA metabolic macrophages and Th1 cells. Annals of the rheumatic diseases (2023)
Elena Pontarini, E Sciacca, F Chowdhury, S Grigoriadou, F Rivellese, W J Murray-Brown, Davide Lucchesi, L Fossati-Jimack, A Nerviani, Wlodzimierz J Krzyzosiak, G M Ghirardi, C Giacomassi, Paul Emery, W F Ng, N Sutcliffe, Colin C Everett, C Fernandez, A R Tappuni, R Seror, X Mariette, R Porcher, G Cavallaro, A Pulvirenti, Gwenny M Verstappen, Lisette de Wolff, S Arends, H Bootsma, Myles J Lewis, Costantino Pitzalis, S J Bowman, M Bombardieri, null null
Serum and tissue biomarkers associated with CRESS and STAR response to B-cell targeted therapy in TRACTISS trial of Sjogren's syndrome. Arthritis & rheumatology (Hoboken, N.J.) (2023)
Myles J Lewis, Costantino Pitzalis
Progress continues in prediction of the response to treatment of RA. Nature reviews. Rheumatology 19 (2) (2023)
Myles J Lewis, Costantino Pitzalis
Progress continues in prediction of the response to treatment of RA. Nature reviews. Rheumatology 19 (2) (2023)
Fan Zhang, Anna Helena Jonsson, Aparna Nathan, Nghia Millard, Michelle Curtis, Qian Xiao, Maria Gutierrez-Arcelus, William Apruzzese, Gerald F M Watts, Dana Weisenfeld, Saba Nayar, Javier Rangel-Moreno, Nida Meednu, Kathryne E Marks, Ian Mantel, Joyce B Kang, Laurie Rumker, Joseph Mears, Kamil Slowikowski, Kathryn Weinand, Dana E Orange, Laura Geraldino-Pardilla, Kevin D Deane, Darren Tabechian, Arnoldas Ceponis, Gary S Firestein, Mark Maybury, Ilfita Sahbudin, Ami Ben-Artzi, Arthur M Mandelin, Alessandra Nerviani, Myles J Lewis, Felice Rivellese, Costantino Pitzalis, Laura B Hughes, Diane Horowitz, Edward DiCarlo, Ellen M Gravallese, Brendan F Boyce, null null, Larry W Moreland, Susan M Goodman, Harris Perlman, V Michael Holers, Katherine P Liao, Andrew Filer, Vivian P Bykerk, Kevin Wei, Deepak A Rao, Laura T Donlin, Jennifer H Anolik, Michael B Brenner, Soumya Raychaudhuri
Deconstruction of rheumatoid arthritis synovium defines inflammatory subtypes. Nature (2023)
Myles J Lewis, Costantino Pitzalis
Progress continues in prediction of the response to treatment of RA. Nature reviews. Rheumatology 19 (2) (2023)
Myles J Lewis, Costantino Pitzalis
Progress continues in prediction of the response to treatment of RA. Nature reviews. Rheumatology 19 (2) (2023)
Jing Wang, Donna Conlon, Felice Rivellese, Alessandra Nerviani, Myles J Lewis, William Housley, Marc C Levesque, Xiaohong Cao, Carolyn Cuff, Andrew Long, Costantino Pitzalis, Melanie C Ruzek
Synovial Inflammatory Pathways Characterize Anti-TNF-Responsive Rheumatoid Arthritis Patients. Arthritis & rheumatology (Hoboken, N.J.) (2022)
Felice Rivellese, Anna E A Surace, Katriona Goldmann, Elisabetta Sciacca, Cankut Cubuk, Giovanni Giorli, Christopher R John, Alessandra Nerviani, Liliane Fossati-Jimack, Georgina Thorborn, Manzoor Ahmed, Edoardo Prediletto, Sarah E Church, Briana M Hudson, Sarah E Warren, Paul M McKeigue, Frances Humby, Michele Bombardieri, Michael R Barnes, Myles J Lewis, Costantino Pitzalis, null null
Rituximab versus tocilizumab in rheumatoid arthritis: synovial biopsy-based biomarker analysis of the phase 4 R4RA randomized trial. Nature medicine 28 (6) (2022)
Aurélie Najm, Félicie Costantino, Stefano Alivernini, Alessia Alunno, Elettra Bianchi, Jacqueline Bignall, Brendan Boyce, Juan D Cañete, Francesco Carubbi, Patrick Durez, João Eurico Fonseca, Søren Andreas Just, Raquel Largo, Antonio Manzo, Mark Maybury, Esperanza Naredo, Carl Orr, Costantino Pitzalis, Felice Rivellese, Vasco C Romão, Jef van Rompay, Sander W Tas, Douglas James Veale, Maria Antonietta D'Agostino, Andrew Filer
EULAR points to consider for minimal reporting requirements in synovial tissue research in rheumatology. Annals of the rheumatic diseases 81 (12) (2022)
Nirmal K Banda, Kevin D Deane, Elizabeth A Bemis, Colin D Strickland, Jennifer A Seifert, Kimberley R Jordan, Katriona Goldmann, Bryan Paul Morgan, Larry W Moreland, Myles J Lewis, Costantino Pitzalis, V Michael Holers
Analysis of Complement Gene Expression, Clinical Associations, and Biodistribution of Complement Proteins in the Synovium of Early Rheumatoid Arthritis Patients Reveals Unique Pathophysiologic Features. Journal of immunology (Baltimore, Md. : 1950) 208 (11) (2022)
Myles J Lewis, Costantino Pitzalis
Progress continues in prediction of the response to treatment of RA. Nature reviews. Rheumatology (2022)
Anne-Sophie Thorup, Danielle Strachan, Sara Caxaria, Blandine Poulet, Bethan L Thomas, Suzanne E Eldridge, Giovanna Nalesso, James R Whiteford, Costantino Pitzalis, Thomas Aigner, Roger Corder, Jessica Bertrand, Francesco Dell'Accio
ROR2 blockade as a therapy for osteoarthritis. Science translational medicine 12 (561) (2021)
Christian Dejaco, Pedro M Machado, Francesco Carubbi, Philipp Bosch, Lene Terslev, Giorgio Tamborrini, Luca Maria Sconfienza, And Carlo Alberto Scirè, Sebastian Ruetten, Jef van Rompay, Fabian Proft, Costantino Pitzalis, Marina Obradov, Rikke Helene Moe, Vasco V Mascarenhas, Clara Malattia, Andrea Sabine Klauser, Alison Kent, Lennart Jans, Wolfgang Hartung, Hilde Berner Hammer, Christina Duftner, Peter V Balint, Alessia Alunno, Xenofon Baraliakos
EULAR Points to Consider for the use of imaging to guide interventional procedures in patients with rheumatic and musculoskeletal diseases (RMDs). Annals of the rheumatic diseases (2021)
Giorgia Fanelli, Marco Romano, Estefanía Nova-Lampeti, Mariana Werner Sunderland, Alessandra Nerviani, Cristiano Scotta, Michele Bombardieri, Sergio A Quezada, Steven H Sacks, Randolph J Noelle, Costantino Pitzalis, Robert I Lechler, Giovanna Lombardi, Pablo D Becker
PD-L1 signaling on human memory CD4+ T cells induces a regulatory phenotype. PLoS biology 19 (4) (2021)
Suzanne E Eldridge, Aida Barawi, Hui Wang, Anke J Roelofs, Magdalena K Kaneva, Zeyu Guan, Helen Lydon, Bethan L Thomas, Anne-Sophie Thorup, Beatriz F Fernandez, Sara Caxaria, Danielle Strachan, Ahmed Ali, Kanatheepan Shanmuganathan, Costantino Pitzalis, James R Whiteford, Frances Henson, Andrew W McCaskie, Cosimo De Bari, Francesco Dell'Accio
Agrin induces long-term osteochondral regeneration by supporting repair morphogenesis. Science translational medicine 12 (559) (2021)
Alessandra Nerviani, Marie-Astrid Boutet, Wang Sin Gina Tan, Katriona Goldmann, Nirupam Purkayastha, Tamas Ajtos Lajtos, Rebecca Hands, Myles J Lewis, Stephen Kelly, Costantino Pitzalis
IL-23 skin and joint profiling in psoriatic arthritis: novel perspectives in understanding clinical responses to IL-23 inhibitors. Annals of the rheumatic diseases 80 (5) (2020)
Elena Pontarini, William James Murray-Brown, Cristina Croia, Davide Lucchesi, James P Conway, Felice Rivellese, Liliane Fossati-Jimack, Elisa Astorri, Edoardo Prediletto, Elisa Corsiero, Francesca Romana Delvecchio, Rachel Coleby, Eva Gelbhardt, Aurora Bono, Chiara Baldini, Ilaria Puxeddu, Roberto Caporali, Roberto Giacomelli, Francesca Barone, Benjamin A Fisher, Simon J Bowman, Serena Colafrancesco, Roberta Priori, Nurhan Sutcliffe, Stephen Challacombe, Gianluca Carlesso, Anwar R Tappuni, Costantino Pitzalis, Michele Bombardieri
Unique expansion of IL-21+ Tfh and Tph cells under control of ICOS identifies Sjögren's syndrome with ectopic germinal centres and MALT lymphoma. Annals of the rheumatic diseases 79 (12) (2020)
Mattias N D Svensson, Martina Zoccheddu, Shen Yang, Gyrid Nygaard, Christian Secchi, Karen M Doody, Kamil Slowikowski, Fumitaka Mizoguchi, Frances Humby, Rebecca Hands, Eugenio Santelli, Cristiano Sacchetti, Kuninobu Wakabayashi, Dennis J Wu, Christopher Barback, Rizi Ai, Wei Wang, Gary P Sims, Piotr Mydel, Tsuyoshi Kasama, David L Boyle, Francesco Galimi, David Vera, Michel L Tremblay, Soumya Raychaudhuri, Michael B Brenner, Gary S Firestein, Costantino Pitzalis, Anna-Karin Hultgård Ekwall, Stephanie M Stanford, Nunzio Bottini
Synoviocyte-targeted therapy synergizes with TNF inhibition in arthritis reversal. Science advances 6 (26) (2020)
Thomas Wj Huizinga, V Michael Holers, Jennifer Anolik, Michael B Brenner, Christopher Dominic Buckley, Vivian Bykerk, Sean E Connolly, Kevin D Deane, Jianping Guo, Martin Hodge, Steve Hoffmann, Frank Nestle, Costantino Pitzalis, Soumya Raychaudhuri, Kazuhiko Yamamoto, Zhanguo Li, Lars Klareskog
Disruptive innovation in rheumatology: new networks of global public-private partnerships are needed to take advantage of scientific progress. Annals of the rheumatic diseases 79 (5) (2020)
Stefano Alivernini, Lucy MacDonald, Aziza Elmesmari, Samuel Finlay, Barbara Tolusso, Maria Rita Gigante, Luca Petricca, Clara Di Mario, Laura Bui, Simone Perniola, Moustafa Attar, Marco Gessi, Anna Laura Fedele, Sabarinadh Chilaka, Domenico Somma, Stephen N Sansom, Andrew Filer, Charles McSharry, Neal L Millar, Kristina Kirschner, Alessandra Nerviani, Myles J Lewis, Costantino Pitzalis, Andrew R Clark, Gianfranco Ferraccioli, Irina A Udalova, Christopher Dominic Buckley, Elisa Gremese, Iain B McInnes, Thomas Dan Otto, Mariola Kurowska-Stolarska
Distinct synovial tissue macrophage subsets regulate inflammation and remission in rheumatoid arthritis. Nature medicine 26 (8) (2020)
Davide Lucchesi, Rachel Coleby, Elena Pontarini, Edoardo Prediletto, Felice Rivellese, David G Hill, Alicia Derrac Soria, Simon A Jones, Ian R Humphreys, Nurhan Sutcliffe, Anwar R Tappuni, Costantino Pitzalis, Gareth W Jones, Michele Bombardieri
Impaired Interleukin-27-Mediated Control of CD4+ T Cell Function Impact on Ectopic Lymphoid Structure Formation in Patients With Sjögren's Syndrome. Arthritis & rheumatology (Hoboken, N.J.) 72 (9) (2020)
Svetlana Cherlin, Myles J Lewis, Darren Plant, Nisha Nair, Katriona Goldmann, Evan Tzanis, Michael R Barnes, Paul McKeigue, Jennifer H Barrett, Costantino Pitzalis, Anne Barton, null null, Heather J Cordell
Investigation of genetically regulated gene expression and response to treatment in rheumatoid arthritis highlights an association between IL18RAP expression and treatment response. Annals of the rheumatic diseases 79 (11) (2020)
Costantino Pitzalis, Ernest H S Choy, Maya H Buch
Transforming clinical trials in rheumatology: towards patient-centric precision medicine. Nature reviews. Rheumatology 16 (10) (2020)
Esteban Alberto Gomez, Romain A Colas, Patricia R Souza, Rebecca Hands, Myles J Lewis, Conrad Bessant, Costantino Pitzalis, Jesmond Dalli
Blood pro-resolving mediators are linked with synovial pathology and are predictive of DMARD responsiveness in rheumatoid arthritis. Nature communications 11 (1) (2020)
Elisa Corsiero, Emanuela Carlotti, Lucas Jagemann, Mauro Perretti, Costantino Pitzalis, Michele Bombardieri
H and L Chain Affinity Maturation and/or Fab N-Glycosylation Influence Immunoreactivity toward Neutrophil Extracellular Trap Antigens in Rheumatoid Arthritis Synovial B Cell Clones. Journal of immunology (Baltimore, Md. : 1950) 204 (9) (2020)
Angel Bottini, Dennis J Wu, Rizi Ai, Michelle Le Roux, Beatrix Bartok, Michele Bombardieri, Karen M Doody, Vida Zhang, Cristiano Sacchetti, Martina Zoccheddu, Ana Lonic, Xiaochun Li, David L Boyle, Deepa Hammaker, Tzu-Ching Meng, Lin Liu, Maripat Corr, Stephanie M Stanford, Myles J Lewis, Wei Wang, Gary S Firestein, Yeesim Khew-Goodall, Costantino Pitzalis, Nunzio Bottini
PTPN14 phosphatase and YAP promote TGFβ signalling in rheumatoid synoviocytes. Annals of the rheumatic diseases 78 (5) (2019)
Gloria Lliso-Ribera, Frances Humby, Myles J Lewis, Alessandra Nerviani, Daniele Mauro, Felice Rivellese, Stephen Kelly, Rebecca Hands, Fabiola Bene, Nandhini Ramamoorthi, Jason A Hackney, Alberto Cauli, Ernest H Choy, Andrew Filer, Peter C Taylor, Iain McInnes, Michael J Townsend, Costantino Pitzalis
Synovial tissue signatures enhance clinical classification and prognostic/treatment response algorithms in early inflammatory arthritis and predict requirement for subsequent biological therapy: results from the pathobiology of early arthritis cohort (PEAC). Annals of the rheumatic diseases 78 (12) (2019)
Felice Rivellese, Francesca Wanda Rossi, Maria Rosaria Galdiero, Costantino Pitzalis, Amato de Paulis
Mast Cells in Early Rheumatoid Arthritis. International journal of molecular sciences 20 (8) (2019)
Frances Humby, Myles J Lewis, Michael J Townsend, Costantino Pitzalis
Response to: 'Synovial cellular and molecular signatures stratify clinical response to csDMARD therapy and predict radiographic progression in early rheumatoid arthritis patients' by Buch et al. Annals of the rheumatic diseases 79 (11) (2019)
Irene Mattiola, Federica Tomay, Maria De Pizzol, Rita Silva-Gomes, Benedetta Savino, Tamara Gulic, Andrea Doni, Silvia Lonardi, Marie Astrid Boutet, Alessandra Nerviani, Roberta Carriero, Martina Molgora, Matteo Stravalaci, Diego Morone, Irina N Shalova, Yunquin Lee, Subhra K Biswas, Giovanna Mantovani, Marina Sironi, Costantino Pitzalis, William Vermi, Barbara Bottazzi, Alberto Mantovani, Massimo Locati
The macrophage tetraspan MS4A4A enhances dectin-1-dependent NK cell-mediated resistance to metastasis. Nature immunology 20 (8) (2019)
Fan Zhang, Kevin Wei, Kamil Slowikowski, Chamith Y Fonseka, Deepak A Rao, Stephen Kelly, Susan M Goodman, Darren Tabechian, Laura B Hughes, Karen Salomon-Escoto, Gerald F M Watts, Anna Helena Jonsson, Javier Rangel-Moreno, Nida Meednu, Cristina Rozo, William Apruzzese, Thomas M Eisenhaure, David J Lieb, David L Boyle, Arthur M Mandelin, null null, Brendan F Boyce, Edward DiCarlo, Ellen M Gravallese, Peter K Gregersen, Larry Moreland, Gary S Firestein, Nir Hacohen, Chad Nusbaum, James A Lederer, Harris Perlman, Costantino Pitzalis, Andrew Filer, V Michael Holers, Vivian P Bykerk, Laura T Donlin, Jennifer H Anolik, Michael B Brenner, Soumya Raychaudhuri
Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry. Nature immunology 20 (7) (2019)
Frances Humby, Myles J Lewis, Nandhini Ramamoorthi, Jason A Hackney, Michael R Barnes, Michele Bombardieri, A Francesca Setiadi, Stephen Kelly, Fabiola Bene, Maria DiCicco, Sudeh Riahi, Vidalba Rocher, Nora Ng, Ilias Lazarou, Rebecca Hands, Désirée Mfm van der Heijde, Robert B M Landewé, Annette van der Helm-van Mil, Alberto Cauli, Iain McInnes, Christopher Dominic Buckley, Ernest H Choy, Peter C Taylor, Michael J Townsend, Costantino Pitzalis
Synovial cellular and molecular signatures stratify clinical response to csDMARD therapy and predict radiographic progression in early rheumatoid arthritis patients. Annals of the rheumatic diseases 78 (6) (2019)
Javier Rodríguez-Ubreva, Carlos de la Calle-Fabregat, Tianlu Li, Laura Ciudad, Maria L Ballestar, Francesc Català-Moll, Octavio Morante-Palacios, Antonio Garcia-Gomez, Raquel Celis, Frances Humby, Alessandra Nerviani, Javier Martin, Costantino Pitzalis, Juan D Cañete, Esteban Ballestar
Inflammatory cytokines shape a changing DNA methylome in monocytes mirroring disease activity in rheumatoid arthritis. Annals of the rheumatic diseases 78 (11) (2019)
Jason P Twohig, Ana Cardus Figueras, Robert Andrews, Florian Wiede, Benjamin C Cossins, Alicia Derrac Soria, Myles J Lewis, Michael J Townsend, David Millrine, Jasmine Li, David G Hill, Javier Uceda Fernandez, Xiao Liu, Barbara Szomolay, Christopher J Pepper, Philip R Taylor, Costantino Pitzalis, Tony Tiganis, Nigel M Williams, Gareth W Jones, Simon A Jones
Activation of naïve CD4+ T cells re-tunes STAT1 signaling to deliver unique cytokine responses in memory CD4+ T cells. Nature immunology 20 (4) (2019)
Athina Spiliopoulou, Marco Colombo, Darren Plant, Nisha Nair, Jing Cui, Marieke Jh Coenen, Katsunori Ikari, Hisashi Yamanaka, Saedis Saevarsdottir, Leonid Padyukov, S Louis Bridges, Robert P Kimberly, Yukinori Okada, Piet L Cm van Riel, Gertjan Wolbink, Irene E van der Horst-Bruinsma, Niek de Vries, Paul P Tak, Koichiro Ohmura, Helena Canhão, Henk-Jan Guchelaar, Tom Wj Huizinga, Lindsey A Criswell, Soumya Raychaudhuri, Michael E Weinblatt, Anthony G Wilson, Xavier Mariette, John D Isaacs, Ann W Morgan, Costantino Pitzalis, Anne Barton, Paul McKeigue
Association of response to TNF inhibitors in rheumatoid arthritis with quantitative trait loci for CD40 and CD39. Annals of the rheumatic diseases 78 (8) (2019)
Emma R Dorris, Simon J Tazzyman, John Moylett, Nandhini Ramamoorthi, Jason A Hackney, Michael Townsend, Munitta Muthana, Myles J Lewis, Costantino Pitzalis, Anthony G Wilson
The Autoimmune Susceptibility Gene C5orf30 Regulates Macrophage-Mediated Resolution of Inflammation. Journal of immunology (Baltimore, Md. : 1950) 202 (4) (2019)
Elisa Corsiero, Lucas Jagemann, Mauro Perretti, Costantino Pitzalis, Michele Bombardieri
Characterization of a Synovial B Cell-Derived Recombinant Monoclonal Antibody Targeting Stromal Calreticulin in the Rheumatoid Joints. Journal of immunology (Baltimore, Md. : 1950) 201 (5) (2018)
Magdalena K Kaneva, Karin V Greco, Sarah E Headland, Trinidad Montero-Melendez, Prashant Mori, Kevin Greenslade, Costantino Pitzalis, Adrian Moore, Mauro Perretti
Identification of Novel Chondroprotective Mediators in Resolving Inflammatory Exudates. Journal of immunology (Baltimore, Md. : 1950) 198 (7) (2017)
Joseph C Lownik, Andrea J Luker, Sheela R Damle, Lauren Folgosa Cooley, Riham El Sayed, Andreas Hutloff, Costantino Pitzalis, Rebecca K Martin, Mohey Eldin M El Shikh, Daniel H Conrad
ADAM10-Mediated ICOS Ligand Shedding on B Cells Is Necessary for Proper T Cell ICOS Regulation and T Follicular Helper Responses. Journal of immunology (Baltimore, Md. : 1950) 199 (7) (2017)
Yanxia Guo, Alice M Walsh, Ursula Fearon, Malcolm D Smith, Mihir D Wechalekar, Xuefeng Yin, Suzanne Cole, Carl Orr, Trudy McGarry, Mary Canavan, Stephan Kelly, Tai-An Lin, Xuejun Liu, Susanna M Proudman, Douglas J Veale, Costantino Pitzalis, Sunil Nagpal
CD40L-Dependent Pathway Is Active at Various Stages of Rheumatoid Arthritis Disease Progression. Journal of immunology (Baltimore, Md. : 1950) 198 (11) (2017)

Costantino Pitzalis.css-eqlu8i{font-size:small;padding-left:4px;} (C Pitzalis)

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Costantino Pitzalis (C Pitzalis)