Myles J Lewis (M J Lewis, Myles Lewis)

ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 61

Top Venues

Annals of the rheumatic diseases

Cellular & molecular immunology

Bioinformatics (Oxford, England)

Nature reviews. Rheumatology

Queen Mary University of London

Imperial College London (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Queen Mary University of London Feb 15 2014

United Kingdom

Clinician Scientist Fellow/ Senior Lecturer :: Experimental Medicine & Rheumatology

King's College London Oct 01 2010 - Feb 14 2014

United Kingdom

Senior Research Fellow :: Genetics

Education History

Imperial College London

United Kingdom

PHD :: Hammersmith Hospital

Publications

Alessandra Nerviani, Marie-Astrid Boutet, Giulia Maria Ghirardi, Katriona Goldmann, Elisabetta Sciacca, Felice Rivellese, Elena Pontarini, Edoardo Prediletto, Federico Abatecola, Mattia Caliste, Sara Pagani, Daniele Mauro, Mattia Bellan, Cankut Cubuk, Rachel Lau, Sarah E Church, Briana M Hudson, Frances Humby, Michele Bombardieri, Myles J Lewis, Costantino Pitzalis
Axl and MerTK regulate synovial inflammation and are modulated by IL-6 inhibition in rheumatoid arthritis. Nature communications 15 (1) (2024)
Alessandra Nerviani, Marie-Astrid Boutet, Giulia Maria Ghirardi, Katriona Goldmann, Elisabetta Sciacca, Felice Rivellese, Elena Pontarini, Edoardo Prediletto, Federico Abatecola, Mattia Caliste, Sara Pagani, Daniele Mauro, Mattia Bellan, Cankut Cubuk, Rachel Lau, Sarah E Church, Briana M Hudson, Frances Humby, Michele Bombardieri, Myles J Lewis, Costantino Pitzalis
Axl and MerTK regulate synovial inflammation and are modulated by IL-6 inhibition in rheumatoid arthritis. Nature communications 15 (1) (2024)
Zilong Bai, Nicholas Bartelo, Maryam Aslam, Elisabeth A Murphy, Caryn R Hale, Nathalie E Blachere, Salina Parveen, Edoardo Spolaore, Edward F DiCarlo, Ellen M Gravallese, Melanie H Smith, null null, Mayu O Frank, Caroline S Jiang, Haotan Zhang, Christina Pyrgaki, Myles J Lewis, Shafaq Sikandar, Costantino Pitzalis, Joseph B Lesnak, Khadijah Mazhar, Theodore John Price, Anne-Marie Malfait, Rachel E Miller, Fan Zhang, Susan M Goodman, Robert B Darnell, Fei Wang, Dana E Orange
Synovial fibroblast gene expression is associated with sensory nerve growth and pain in rheumatoid arthritis. Science translational medicine 16 (742) (2024)
Rafael Henkin, Katriona Goldmann, Myles J Lewis, Michael R Barnes
shinyExprPortal: a configurable 'shiny' portal for sharing analysis of molecular expression data. Bioinformatics (Oxford, England) 40 (4) (2024)
Stephanie R Zack, Osama Alzoubi, Neha Satoeya, Kunwar P Singh, Sania Deen, Wes Nijim, Myles J Lewis, Costantino Pitzalis, Nadera Sweiss, Lionel B Ivashkiv, Shiva Shahrara
ANOTHER NOTCH IN THE BELT OF RHEUMATOID ARTHRITIS. Arthritis & rheumatology (Hoboken, N.J.) (2024)
Zilong Bai, Nicholas Bartelo, Maryam Aslam, Elisabeth A Murphy, Caryn R Hale, Nathalie E Blachere, Salina Parveen, Edoardo Spolaore, Edward F DiCarlo, Ellen M Gravallese, Melanie H Smith, null null, Mayu O Frank, Caroline S Jiang, Haotan Zhang, Christina Pyrgaki, Myles J Lewis, Shafaq Sikandar, Costantino Pitzalis, Joseph B Lesnak, Khadijah Mazhar, Theodore John Price, Anne-Marie Malfait, Rachel E Miller, Fan Zhang, Susan M Goodman, Robert B Darnell, Fei Wang, Dana E Orange
Synovial fibroblast gene expression is associated with sensory nerve growth and pain in rheumatoid arthritis. Science translational medicine 16 (742) (2024)
Alessandra Nerviani, Marie-Astrid Boutet, Giulia Maria Ghirardi, Katriona Goldmann, Elisabetta Sciacca, Felice Rivellese, Elena Pontarini, Edoardo Prediletto, Federico Abatecola, Mattia Caliste, Sara Pagani, Daniele Mauro, Mattia Bellan, Cankut Cubuk, Rachel Lau, Sarah E Church, Briana M Hudson, Frances Humby, Michele Bombardieri, Myles J Lewis, Costantino Pitzalis
Axl and MerTK regulate synovial inflammation and are modulated by IL-6 inhibition in rheumatoid arthritis. Nature communications 15 (1) (2024)
Rafael Henkin, Katriona Goldmann, Myles J Lewis, Michael R Barnes
shinyExprPortal: a configurable 'shiny' portal for sharing analysis of molecular expression data. Bioinformatics (Oxford, England) 40 (4) (2024)
Zilong Bai, Nicholas Bartelo, Maryam Aslam, Elisabeth A Murphy, Caryn R Hale, Nathalie E Blachere, Salina Parveen, Edoardo Spolaore, Edward F DiCarlo, Ellen M Gravallese, Melanie H Smith, null null, Mayu O Frank, Caroline S Jiang, Haotan Zhang, Christina Pyrgaki, Myles J Lewis, Shafaq Sikandar, Costantino Pitzalis, Joseph B Lesnak, Khadijah Mazhar, Theodore John Price, Anne-Marie Malfait, Rachel E Miller, Fan Zhang, Susan M Goodman, Robert B Darnell, Fei Wang, Dana E Orange
Synovial fibroblast gene expression is associated with sensory nerve growth and pain in rheumatoid arthritis. Science translational medicine 16 (742) (2024)
Alessandra Nerviani, Marie-Astrid Boutet, Giulia Maria Ghirardi, Katriona Goldmann, Elisabetta Sciacca, Felice Rivellese, Elena Pontarini, Edoardo Prediletto, Federico Abatecola, Mattia Caliste, Sara Pagani, Daniele Mauro, Mattia Bellan, Cankut Cubuk, Rachel Lau, Sarah E Church, Briana M Hudson, Frances Humby, Michele Bombardieri, Myles J Lewis, Costantino Pitzalis
Axl and MerTK regulate synovial inflammation and are modulated by IL-6 inhibition in rheumatoid arthritis. Nature communications 15 (1) (2024)
Stephanie R Zack, Osama Alzoubi, Neha Satoeya, Kunwar P Singh, Sania Deen, Wes Nijim, Myles J Lewis, Costantino Pitzalis, Nadera Sweiss, Lionel B Ivashkiv, Shiva Shahrara
Another Notch in the Belt of Rheumatoid Arthritis. Arthritis & rheumatology (Hoboken, N.J.) (2024)
Zilong Bai, Nicholas Bartelo, Maryam Aslam, Elisabeth A Murphy, Caryn R Hale, Nathalie E Blachere, Salina Parveen, Edoardo Spolaore, Edward F DiCarlo, Ellen M Gravallese, Melanie H Smith, null null, Mayu O Frank, Caroline S Jiang, Haotan Zhang, Christina Pyrgaki, Myles J Lewis, Shafaq Sikandar, Costantino Pitzalis, Joseph B Lesnak, Khadijah Mazhar, Theodore John Price, Anne-Marie Malfait, Rachel E Miller, Fan Zhang, Susan M Goodman, Robert B Darnell, Fei Wang, Dana E Orange
Synovial fibroblast gene expression is associated with sensory nerve growth and pain in rheumatoid arthritis. Science translational medicine 16 (742) (2024)
Rafael Henkin, Katriona Goldmann, Myles J Lewis, Michael R Barnes
shinyExprPortal: a configurable 'shiny' portal for sharing analysis of molecular expression data. Bioinformatics (Oxford, England) 40 (4) (2024)
Zilong Bai, Nicholas Bartelo, Maryam Aslam, Elisabeth A Murphy, Caryn R Hale, Nathalie E Blachere, Salina Parveen, Edoardo Spolaore, Edward F DiCarlo, Ellen M Gravallese, Melanie H Smith, null null, Mayu O Frank, Caroline S Jiang, Haotan Zhang, Christina Pyrgaki, Myles J Lewis, Shafaq Sikandar, Costantino Pitzalis, Joseph B Lesnak, Khadijah Mazhar, Theodore John Price, Anne-Marie Malfait, Rachel E Miller, Fan Zhang, Susan M Goodman, Robert B Darnell, Fei Wang, Dana E Orange
Synovial fibroblast gene expression is associated with sensory nerve growth and pain in rheumatoid arthritis. Science translational medicine 16 (742) (2024)
Elisabetta Sciacca, Salvatore Alaimo, Gianmarco Silluzio, Alfredo Ferro, Vito Latora, Costantino Pitzalis, Alfredo Pulvirenti, Myles J Lewis
DEGGs: an R package with shiny app for the identification of differentially expressed gene-gene interactions in high-throughput sequencing data. Bioinformatics (Oxford, England) 39 (4) (2023)
Anja Meyer, Stephanie R Zack, Wes Nijim, Adel Burgos, Vishwa Patel, Brian Zanotti, Michael V Volin, M Asif Amin, Myles J Lewis, Costantino Pitzalis, Shiva Arami, Joseph A Karam, Nadera J Sweiss, Shiva Shahrara
Metabolic reprogramming by Syntenin-1 directs RA FLS and endothelial cell-mediated inflammation and angiogenesis. Cellular & molecular immunology (2023)
Katriona Goldmann, Athina Spiliopoulou, Andrii Iakovliev, Darren Plant, Nisha Nair, Cankut Cubuk, null null, Paul M McKeigue, Michael R Barnes, Richard B Warren, Costantino Pitzalis, Myles J Lewis
Expression quantitative trait loci analysis in rheumatoid arthritis identifies tissue specific variants associated with severity and outcome. Annals of the rheumatic diseases (2023)
Myles J Lewis, Athina Spiliopoulou, Katriona Goldmann, Costantino Pitzalis, Paul McKeigue, Michael R Barnes
nestedcv: an R package for fast implementation of nested cross-validation with embedded feature selection designed for transcriptomics and high-dimensional data. Bioinformatics advances 3 (1) (2023)
Anja Meyer, Ryan E Sienes, Wes Nijim, Brian Zanotti, Sadiq Umar, Michael V Volin, Katrien Van Raemdonck, Myles J Lewis, Costantino Pitzalis, Shiva Arami, Mina Al-Awqati, Huan J Chang, Pim Jetanalin, Larissa Valor-Méndez, Nadera Sweiss, Shiva Shahrara
Syntenin-1-mediated arthritogenicity is advanced by reprogramming RA metabolic macrophages and Th1 cells. Annals of the rheumatic diseases (2023)
Myles J Lewis, Athina Spiliopoulou, Katriona Goldmann, Costantino Pitzalis, Paul McKeigue, Michael R Barnes
nestedcv: an R package for fast implementation of nested cross-validation with embedded feature selection designed for transcriptomics and high-dimensional data. Bioinformatics advances 3 (1) (2023)
Anja Meyer, Ryan E Sienes, Wes Nijim, Brian Zanotti, Sadiq Umar, Michael V Volin, Katrien Van Raemdonck, Myles J Lewis, Costantino Pitzalis, Shiva Arami, Mina Al-Awqati, Huan J Chang, Pim Jetanalin, Larissa Valor-Méndez, Nadera Sweiss, Shiva Shahrara
Syntenin-1-mediated arthritogenicity is advanced by reprogramming RA metabolic macrophages and Th1 cells. Annals of the rheumatic diseases (2023)
Maximilian Kugler, Mirjam Dellinger, Felix Kartnig, Lena Müller, Teresa Preglej, Leonhard X Heinz, Elisabeth Simader, Lisa Göschl, Stephan E Puchner, Sebastian Weiss, Lisa E Shaw, Matthias Farlik, Wolfgang Weninger, Giulio Superti-Furga, Josef S Smolen, Guenter Steiner, Daniel Aletaha, Hans P Kiener, Myles J Lewis, Costantino Pitzalis, Anela Tosevska, Thomas Karonitsch, Michael Markus Bonelli
Cytokine-directed cellular cross-talk imprints synovial pathotypes in rheumatoid arthritis. Annals of the rheumatic diseases (2023)
Anja Meyer, Ryan E Sienes, Wes Nijim, Brian Zanotti, Sadiq Umar, Michael V Volin, Katrien Van Raemdonck, Myles J Lewis, Costantino Pitzalis, Shiva Arami, Mina Al-Awqati, Huan J Chang, Pim Jetanalin, Larissa Valor-Méndez, Nadera Sweiss, Shiva Shahrara
Syntenin-1-mediated arthritogenicity is advanced by reprogramming RA metabolic macrophages and Th1 cells. Annals of the rheumatic diseases (2023)
Anja Meyer, Stephanie R Zack, Wes Nijim, Adel Burgos, Vishwa Patel, Brian Zanotti, Michael V Volin, M Asif Amin, Myles J Lewis, Costantino Pitzalis, Shiva Arami, Joseph A Karam, Nadera J Sweiss, Shiva Shahrara
Metabolic reprogramming by Syntenin-1 directs RA FLS and endothelial cell-mediated inflammation and angiogenesis. Cellular & molecular immunology 21 (1) (2023)
Anja Meyer, Stephanie R Zack, Wes Nijim, Adel Burgos, Vishwa Patel, Brian Zanotti, Michael V Volin, M Asif Amin, Myles J Lewis, Costantino Pitzalis, Shiva Arami, Joseph A Karam, Nadera J Sweiss, Shiva Shahrara
Metabolic reprogramming by Syntenin-1 directs RA FLS and endothelial cell-mediated inflammation and angiogenesis. Cellular & molecular immunology 21 (1) (2023)
Anja Meyer, Stephanie R Zack, Wes Nijim, Adel Burgos, Vishwa Patel, Brian Zanotti, Michael V Volin, M Asif Amin, Myles J Lewis, Costantino Pitzalis, Shiva Arami, Joseph A Karam, Nadera J Sweiss, Shiva Shahrara
Metabolic reprogramming by Syntenin-1 directs RA FLS and endothelial cell-mediated inflammation and angiogenesis. Cellular & molecular immunology 21 (1) (2023)
Elisabetta Sciacca, Salvatore Alaimo, Gianmarco Silluzio, Alfredo Ferro, Vito Latora, Costantino Pitzalis, Alfredo Pulvirenti, Myles J Lewis
DEGGs: an R package with shiny app for the identification of differentially expressed gene-gene interactions in high-throughput sequencing data. Bioinformatics (Oxford, England) 39 (4) (2023)
Elena Pontarini, E Sciacca, F Chowdhury, S Grigoriadou, F Rivellese, W J Murray-Brown, Davide Lucchesi, L Fossati-Jimack, A Nerviani, Wlodzimierz J Krzyzosiak, G M Ghirardi, C Giacomassi, Paul Emery, W F Ng, N Sutcliffe, Colin C Everett, C Fernandez, A R Tappuni, R Seror, X Mariette, R Porcher, G Cavallaro, A Pulvirenti, Gwenny M Verstappen, Lisette de Wolff, S Arends, H Bootsma, Myles J Lewis, Costantino Pitzalis, S J Bowman, M Bombardieri, null null
Serum and tissue biomarkers associated with CRESS and STAR response to B-cell targeted therapy in TRACTISS trial of Sjogren's syndrome. Arthritis & rheumatology (Hoboken, N.J.) (2023)
Elisabetta Sciacca, Salvatore Alaimo, Gianmarco Silluzio, Alfredo Ferro, Vito Latora, Costantino Pitzalis, Alfredo Pulvirenti, Myles J Lewis
DEGGs: an R package with shiny app for the identification of differentially expressed gene-gene interactions in high-throughput sequencing data. Bioinformatics (Oxford, England) 39 (4) (2023)
Anja Meyer, Stephanie R Zack, Wes Nijim, Adel Burgos, Vishwa Patel, Brian Zanotti, Michael V Volin, M Asif Amin, Myles J Lewis, Costantino Pitzalis, Shiva Arami, Joseph A Karam, Nadera J Sweiss, Shiva Shahrara
Metabolic reprogramming by Syntenin-1 directs RA FLS and endothelial cell-mediated inflammation and angiogenesis. Cellular & molecular immunology (2023)
Anja Meyer, Stephanie R Zack, Wes Nijim, Adel Burgos, Vishwa Patel, Brian Zanotti, Michael V Volin, M Asif Amin, Myles J Lewis, Costantino Pitzalis, Shiva Arami, Joseph A Karam, Nadera J Sweiss, Shiva Shahrara
Metabolic reprogramming by Syntenin-1 directs RA FLS and endothelial cell-mediated inflammation and angiogenesis. Cellular & molecular immunology 21 (1) (2023)
Myles J Lewis, Costantino Pitzalis
Progress continues in prediction of the response to treatment of RA. Nature reviews. Rheumatology 19 (2) (2023)
Elisabetta Sciacca, Salvatore Alaimo, Gianmarco Silluzio, Alfredo Ferro, Vito Latora, Costantino Pitzalis, Alfredo Pulvirenti, Myles J Lewis
DEGGs: an R package with shiny app for the identification of differentially expressed gene-gene interactions in high-throughput sequencing data. Bioinformatics (Oxford, England) 39 (4) (2023)
Myles J Lewis, Costantino Pitzalis
Progress continues in prediction of the response to treatment of RA. Nature reviews. Rheumatology 19 (2) (2023)
Anja Meyer, Stephanie R Zack, Wes Nijim, Adel Burgos, Vishwa Patel, Brian Zanotti, Michael V Volin, M Asif Amin, Myles J Lewis, Costantino Pitzalis, Shiva Arami, Joseph A Karam, Nadera J Sweiss, Shiva Shahrara
Metabolic reprogramming by Syntenin-1 directs RA FLS and endothelial cell-mediated inflammation and angiogenesis. Cellular & molecular immunology 21 (1) (2023)
Fan Zhang, Anna Helena Jonsson, Aparna Nathan, Nghia Millard, Michelle Curtis, Qian Xiao, Maria Gutierrez-Arcelus, William Apruzzese, Gerald F M Watts, Dana Weisenfeld, Saba Nayar, Javier Rangel-Moreno, Nida Meednu, Kathryne E Marks, Ian Mantel, Joyce B Kang, Laurie Rumker, Joseph Mears, Kamil Slowikowski, Kathryn Weinand, Dana E Orange, Laura Geraldino-Pardilla, Kevin D Deane, Darren Tabechian, Arnoldas Ceponis, Gary S Firestein, Mark Maybury, Ilfita Sahbudin, Ami Ben-Artzi, Arthur M Mandelin, Alessandra Nerviani, Myles J Lewis, Felice Rivellese, Costantino Pitzalis, Laura B Hughes, Diane Horowitz, Edward DiCarlo, Ellen M Gravallese, Brendan F Boyce, null null, Larry W Moreland, Susan M Goodman, Harris Perlman, V Michael Holers, Katherine P Liao, Andrew Filer, Vivian P Bykerk, Kevin Wei, Deepak A Rao, Laura T Donlin, Jennifer H Anolik, Michael B Brenner, Soumya Raychaudhuri
Deconstruction of rheumatoid arthritis synovium defines inflammatory subtypes. Nature (2023)
Myles J Lewis, Athina Spiliopoulou, Katriona Goldmann, Costantino Pitzalis, Paul McKeigue, Michael R Barnes
nestedcv: an R package for fast implementation of nested cross-validation with embedded feature selection designed for transcriptomics and high-dimensional data. Bioinformatics advances 3 (1) (2023)
Zilong Bai, Nicholas Bartelo, Maryam Aslam, Caryn Hale, Nathalie E Blachere, Salina Parveen, Edoardo Spolaore, Edward DiCarlo, Ellen Gravallese, Melanie H Smith, null null, Mayu O Frank, Caroline S Jiang, Haotan Zhang, Myles J Lewis, Shafaq Sikandar, Costantino Pitzalis, Anne-Marie Malfait, Rachel E Miller, Fan Zhang, Susan Goodman, Robert B Darnell, Fei Wang, Dana E Orange
Machine Learning Reveals Synovial Fibroblast Genes Associated with Pain Affect Sensory Nerve Growth in Rheumatoid Arthritis. medRxiv : the preprint server for health sciences (2023)
Anja Meyer, Stephanie R Zack, Wes Nijim, Adel Burgos, Vishwa Patel, Brian Zanotti, Michael V Volin, M Asif Amin, Myles J Lewis, Costantino Pitzalis, Shiva Arami, Joseph A Karam, Nadera J Sweiss, Shiva Shahrara
Metabolic reprogramming by Syntenin-1 directs RA FLS and endothelial cell-mediated inflammation and angiogenesis. Cellular & molecular immunology 21 (1) (2023)
Myles J Lewis, Costantino Pitzalis
Progress continues in prediction of the response to treatment of RA. Nature reviews. Rheumatology 19 (2) (2023)
Myles J Lewis, Costantino Pitzalis
Progress continues in prediction of the response to treatment of RA. Nature reviews. Rheumatology 19 (2) (2023)
Jing Wang, Donna Conlon, Felice Rivellese, Alessandra Nerviani, Myles J Lewis, William Housley, Marc C Levesque, Xiaohong Cao, Carolyn Cuff, Andrew Long, Costantino Pitzalis, Melanie C Ruzek
Synovial Inflammatory Pathways Characterize Anti-TNF-Responsive Rheumatoid Arthritis Patients. Arthritis & rheumatology (Hoboken, N.J.) (2022)
Felice Rivellese, Anna E A Surace, Katriona Goldmann, Elisabetta Sciacca, Cankut Cubuk, Giovanni Giorli, Christopher R John, Alessandra Nerviani, Liliane Fossati-Jimack, Georgina Thorborn, Manzoor Ahmed, Edoardo Prediletto, Sarah E Church, Briana M Hudson, Sarah E Warren, Paul M McKeigue, Frances Humby, Michele Bombardieri, Michael R Barnes, Myles J Lewis, Costantino Pitzalis, null null
Rituximab versus tocilizumab in rheumatoid arthritis: synovial biopsy-based biomarker analysis of the phase 4 R4RA randomized trial. Nature medicine 28 (6) (2022)
Nirmal K Banda, Kevin D Deane, Elizabeth A Bemis, Colin D Strickland, Jennifer A Seifert, Kimberley R Jordan, Katriona Goldmann, Bryan Paul Morgan, Larry W Moreland, Myles J Lewis, Costantino Pitzalis, V Michael Holers
Analysis of Complement Gene Expression, Clinical Associations, and Biodistribution of Complement Proteins in the Synovium of Early Rheumatoid Arthritis Patients Reveals Unique Pathophysiologic Features. Journal of immunology (Baltimore, Md. : 1950) 208 (11) (2022)
Myles J Lewis, Costantino Pitzalis
Progress continues in prediction of the response to treatment of RA. Nature reviews. Rheumatology (2022)
Felice Rivellese, Sotiria Manou-Stathopoulou, Daniele Mauro, Katriona Goldmann, Debasish Pyne, Ravindra Rajakariar, Patrick Gordon, Peter Schafer, Michele Bombardieri, Costantino Pitzalis, Myles J Lewis
Effects of targeting the transcription factors Ikaros and Aiolos on B cell activation and differentiation in systemic lupus erythematosus. Lupus science & medicine 8 (1) (2021)
Federico Colombo, Elisa Corsiero, Myles J Lewis, Costantino Pitzalis
Generation of restriction endonucleases barcode map to trace SARS-CoV-2 origin and evolution. Scientific reports 11 (1) (2021)
Alessandra Nerviani, Marie-Astrid Boutet, Wang Sin Gina Tan, Katriona Goldmann, Nirupam Purkayastha, Tamas Ajtos Lajtos, Rebecca Hands, Myles J Lewis, Stephen Kelly, Costantino Pitzalis
IL-23 skin and joint profiling in psoriatic arthritis: novel perspectives in understanding clinical responses to IL-23 inhibitors. Annals of the rheumatic diseases 80 (5) (2020)
Stefano Alivernini, Lucy MacDonald, Aziza Elmesmari, Samuel Finlay, Barbara Tolusso, Maria Rita Gigante, Luca Petricca, Clara Di Mario, Laura Bui, Simone Perniola, Moustafa Attar, Marco Gessi, Anna Laura Fedele, Sabarinadh Chilaka, Domenico Somma, Stephen N Sansom, Andrew Filer, Charles McSharry, Neal L Millar, Kristina Kirschner, Alessandra Nerviani, Myles J Lewis, Costantino Pitzalis, Andrew R Clark, Gianfranco Ferraccioli, Irina A Udalova, Christopher Dominic Buckley, Elisa Gremese, Iain B McInnes, Thomas Dan Otto, Mariola Kurowska-Stolarska
Distinct synovial tissue macrophage subsets regulate inflammation and remission in rheumatoid arthritis. Nature medicine 26 (8) (2020)
Sara Pagani, Mattia Bellan, Daniele Mauro, Luigi Mario Castello, Gian Carlo Avanzi, Myles J Lewis, Pier Paolo Sainaghi, Costantino Pitzalis, Alessandra Nerviani
New Insights into the Role of Tyro3, Axl, and Mer Receptors in Rheumatoid Arthritis. Disease markers 2020 (2020)
Felice Rivellese, Frances Humby, S Bugatti, Liliane Fossati-Jimack, H Rizvi, Davide Lucchesi, G Lliso-Ribera, A Nerviani, R E Hands, G Giorli, B Frias, G Thorborn, Wlodzimierz J Krzyzosiak, C John, K Goldmann, Myles J Lewis, A Manzo, M Bombardieri, C Pitzalis, null null
B Cell Synovitis and Clinical Phenotypes in Rheumatoid Arthritis: Relationship to Disease Stages and Drug Exposure. Arthritis & rheumatology (Hoboken, N.J.) 72 (5) (2020)
Svetlana Cherlin, Myles J Lewis, Darren Plant, Nisha Nair, Katriona Goldmann, Evan Tzanis, Michael R Barnes, Paul McKeigue, Jennifer H Barrett, Costantino Pitzalis, Anne Barton, null null, Heather J Cordell
Investigation of genetically regulated gene expression and response to treatment in rheumatoid arthritis highlights an association between IL18RAP expression and treatment response. Annals of the rheumatic diseases 79 (11) (2020)
Esteban Alberto Gomez, Romain A Colas, Patricia R Souza, Rebecca Hands, Myles J Lewis, Conrad Bessant, Costantino Pitzalis, Jesmond Dalli
Blood pro-resolving mediators are linked with synovial pathology and are predictive of DMARD responsiveness in rheumatoid arthritis. Nature communications 11 (1) (2020)
Christopher R John, David Watson, Dominic Russ, Katriona Goldmann, Michael Ehrenstein, Costantino Pitzalis, Myles J Lewis, Michael R Barnes
M3C: Monte Carlo reference-based consensus clustering. Scientific reports 10 (1) (2020)
Myles J Lewis, Michael R Barnes
RNA sequencing and machine learning as molecular scalpels. Nature reviews. Rheumatology 14 (7) (2019)
Angel Bottini, Dennis J Wu, Rizi Ai, Michelle Le Roux, Beatrix Bartok, Michele Bombardieri, Karen M Doody, Vida Zhang, Cristiano Sacchetti, Martina Zoccheddu, Ana Lonic, Xiaochun Li, David L Boyle, Deepa Hammaker, Tzu-Ching Meng, Lin Liu, Maripat Corr, Stephanie M Stanford, Myles J Lewis, Wei Wang, Gary S Firestein, Yeesim Khew-Goodall, Costantino Pitzalis, Nunzio Bottini
PTPN14 phosphatase and YAP promote TGFβ signalling in rheumatoid synoviocytes. Annals of the rheumatic diseases 78 (5) (2019)
Gloria Lliso-Ribera, Frances Humby, Myles J Lewis, Alessandra Nerviani, Daniele Mauro, Felice Rivellese, Stephen Kelly, Rebecca Hands, Fabiola Bene, Nandhini Ramamoorthi, Jason A Hackney, Alberto Cauli, Ernest H Choy, Andrew Filer, Peter C Taylor, Iain McInnes, Michael J Townsend, Costantino Pitzalis
Synovial tissue signatures enhance clinical classification and prognostic/treatment response algorithms in early inflammatory arthritis and predict requirement for subsequent biological therapy: results from the pathobiology of early arthritis cohort (PEAC). Annals of the rheumatic diseases 78 (12) (2019)
Frances Humby, Myles J Lewis, Michael J Townsend, Costantino Pitzalis
Response to: 'Synovial cellular and molecular signatures stratify clinical response to csDMARD therapy and predict radiographic progression in early rheumatoid arthritis patients' by Buch et al. Annals of the rheumatic diseases 79 (11) (2019)
Frances Humby, Myles J Lewis, Nandhini Ramamoorthi, Jason A Hackney, Michael R Barnes, Michele Bombardieri, A Francesca Setiadi, Stephen Kelly, Fabiola Bene, Maria DiCicco, Sudeh Riahi, Vidalba Rocher, Nora Ng, Ilias Lazarou, Rebecca Hands, Désirée Mfm van der Heijde, Robert B M Landewé, Annette van der Helm-van Mil, Alberto Cauli, Iain McInnes, Christopher Dominic Buckley, Ernest H Choy, Peter C Taylor, Michael J Townsend, Costantino Pitzalis
Synovial cellular and molecular signatures stratify clinical response to csDMARD therapy and predict radiographic progression in early rheumatoid arthritis patients. Annals of the rheumatic diseases 78 (6) (2019)
Jason P Twohig, Ana Cardus Figueras, Robert Andrews, Florian Wiede, Benjamin C Cossins, Alicia Derrac Soria, Myles J Lewis, Michael J Townsend, David Millrine, Jasmine Li, David G Hill, Javier Uceda Fernandez, Xiao Liu, Barbara Szomolay, Christopher J Pepper, Philip R Taylor, Costantino Pitzalis, Tony Tiganis, Nigel M Williams, Gareth W Jones, Simon A Jones
Activation of naïve CD4+ T cells re-tunes STAT1 signaling to deliver unique cytokine responses in memory CD4+ T cells. Nature immunology 20 (4) (2019)
Emma R Dorris, Simon J Tazzyman, John Moylett, Nandhini Ramamoorthi, Jason A Hackney, Michael Townsend, Munitta Muthana, Myles J Lewis, Costantino Pitzalis, Anthony G Wilson
The Autoimmune Susceptibility Gene C5orf30 Regulates Macrophage-Mediated Resolution of Inflammation. Journal of immunology (Baltimore, Md. : 1950) 202 (4) (2019)

Myles J Lewis.css-eqlu8i{font-size:small;padding-left:4px;} (M J Lewis, Myles Lewis)

Publication Activity (10 Years)

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Myles J Lewis (M J Lewis, Myles Lewis)