A prospective, phase II, single-centre, cross-sectional, randomised study investigating Dehydroepiandrosterone supplementation and its Profile in Trauma: ADaPT.
Conor BentleyClaire PotterKamal Makram YakoubKristian BrockVictoria HomerEmma TomanAngela E TaylorFozia ShaheenLorna C GilliganAmrita AthwalDarren BartonRonald CarreraKatie YoungAmisha DesaiKirsty McGeeChristos ErmogenousGurneet SurCarolyn A GreigJon HazeldineWiebke ArltJanet M LordMark A FosterPublished in: BMJ open (2021)
The study recruited its first patient on 2 April 2019 and held its first data monitoring committee on 8 November 2019. DHEA dosing has increased to 100 mg in both male cohorts and remains on 50 mg in across all female groups.